Results 121 to 130 of about 1,355 (256)

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

A scoping review of EFL learners' interlanguage pragmatic development. [PDF]

PLoS One
Li H, Kasim ZM, Ang LH.
europepmc   +1 more source

Reflections on Traceability for Visualization Research

Computer Graphics Forum, EarlyView.
Abstract Decades of advocacy for reproducibility and replication have advanced open, transparent practices in the sciences. However, traditional notions of reproducibility fit poorly with design‐oriented visualization research, where insights emerge through subjective, situated, and iterative work.
J. Rogers, D. Akbaba, J. S. Brown, A. Lex, M. Meyer   +4 more
wiley   +1 more source

The role of pragmatic mechanisms in referential communication and categorization: An emergent communication model. [PDF]

PLoS Comput Biol
Kobrock K, Ohmer X, Bruni E, Gotzner N.
europepmc   +1 more source

Neural correlates of language disfunction in psychiatric disorders: a developmental perspective. [PDF]

J Neural Transm (Vienna)
Manfredi M, Iliopoulos F, Hehl NL, Walitza S, Giroud N.   +4 more
europepmc   +1 more source

Australian healthcare professionals' perspectives and experiences on screening and monitoring islet autoimmunity: A qualitative exploration

Diabetic Medicine, EarlyView.
Abstract Aims Islet autoantibodies characterise a period of immune‐mediated destruction preceding clinical (symptomatic) type 1 diabetes. Screening and monitoring programmes for islet autoimmunity are being planned and implemented globally. The perspectives and experiences of healthcare professionals working in paediatric screening and monitoring of ...
Mia Majstorovic, Kelly J. McGorm, John M. Wentworth, Alyssa Sawyer, Melissa Oxlad, Jennifer J. Couper   +5 more
wiley   +1 more source

Pragmatic Competence Modulates Counterfactual Emotion Processing: Eye-Tracking Evidence from Mandarin Chinese. [PDF]

Behav Sci (Basel)
Dai H, Xu Y, Bian J.
europepmc   +1 more source

The Mechanics of Critique

European Journal of Philosophy, EarlyView.
Abstract Immanent critique is often presented as a distinctive approach to political and social philosophy. But Rachel Fraser argues that immanent critique cannot satisfy three plausible criteria that characterise it as a distinctive approach: it cannot be normatively significant, social, and make no appeal to external standards.
Michael O'Connor
wiley   +1 more source

The Role of Social Media Interaction in Developing Intercultural Digital Communication Competence: A Systematic Literature Review. [PDF]

Behav Sci (Basel)
Zhang C, Husain S, Mamat R.
europepmc   +1 more source

Organisational dehumanisation: Authoritativeness as remedy

European Management Review, EarlyView.
Abstract According to orthodoxy, the human relations movement was a watershed in rehumanising scientifically managed workplaces. In the wake of such purported reform, pundits (theorists and practitioners alike) have typically taken for granted that 21st century approaches to workplace superintendence, birthed in the wake of the Hawthorne Studies and ...
Jean‐Etienne Joullié, Anthony M. Gould, Jeffrey Muldoon   +2 more
wiley   +1 more source