Network medicine and systems pharmacology approaches to predicting adverse drug effects
British Journal of Pharmacology, EarlyView.Identifying and understanding the relationships between drug intake and adverse effects that can occur due to inadvertent molecular interactions between drugs and targets is a difficult task, especially considering the numerous variables that can influence the onset of such events.
Alessio Funari +2 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez +13 more
wiley +1 more source
Prolongation of rate-corrected QT interval during phenol-croton oil peels [PDF]
, 2017 Carlos Gustavo Wambier +5 more
openalex +1 more source
Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency
Clinical Genetics, EarlyView.We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou +3 more
wiley +1 more source
Moxifloxacin Does Increase the Corrected QT Interval [PDF]
Clinical Infectious Diseases, 2001 C M, White, E M, Grant, R, Quintiliani
openaire +2 more sources
Environmentally adjusted productivity growth and shadow prices for dairy farms
Canadian Journal of Agricultural Economics/Revue canadienne d'agroeconomie, EarlyView.Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal +2 more
wiley +1 more source
Prolonged Corrected QT Interval in Patients with Myotonic Dystrophy Type 1 [PDF]
, 2013 Kang Min Park +5 more
openalex +1 more source
Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. [PDF]
, 2019 The cardiac transcription factor (TF) gene NKX2-5 has been associated with electrocardiographic (EKG) traits through genome-wide association studies (GWASs), but the extent to which differential binding of NKX2-5 at common regulatory variants contributes
Benaglio, Paola +17 more
core
Systematic Review and Meta‐Analysis of Mortality in Patients With Anorexia Nervosa
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) has one of the highest mortality rates among psychiatric disorders. This systematic review and meta‐analysis examined the all‐cause mortality of AN patients compared to the general population using the standardized mortality ratio (SMR).
Eric Tsz‐Him Lai +10 more
wiley +1 more source
Corrected QT interval in cirrhosis: A systematic review and meta-analysis. [PDF]
World J Hepatol, 2023 Papadopoulos VP, Mimidis K.
europepmc +1 more source