Heritability of Tpeak-Tend interval and T-wave amplitude: a twin study [PDF]
Background— Tpeak-Tend interval (TpTe) and T-wave amplitude (Tamp) carry diagnostic and prognostic information regarding cardiac morbidity and mortality. Heart rate and QT interval are known to be heritable traits.
Budtz-Jørgensen, Esben +4 more
core +1 more source
QT Indexes in Cirrhotic Patients: Relationship with Clinical Variables and Potential Diagnostic Predictive Value. [PDF]
BACKGROUND AND AIMS: A wide spectrum of cardiovascular changes characterizes cirrhosis, ranging from subclinical alterations to hyperkinetic syndrome.
BUTTA', Carmelo +11 more
core +1 more source
The QT and Corrected QT Interval in Recovery After Exercise in Children [PDF]
Background— Prolongation of the QT interval after exercise can be used to help diagnose long-QT syndrome, especially when the resting QT interval is borderline. The aim of this study was to determine the normal ranges for QT and corrected QT in the recovery phase after exercise in children ...
Berger, Wouter Rudolph +5 more
openaire +3 more sources
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi +21 more
wiley +1 more source
Electrocardiographic T-wave peak-to-end interval for hypoglycaemia detection. [PDF]
Electrocardiographic T wave peak-to-end interval (TpTe) is one parameter of T wave morphology, which contains indicators for hypoglycaemia. This paper shows the corrected TpTe (TpTe(c)) interval as one of the inputs contributing to detect hypoglycaemia ...
Nguyen, HT, Nuryani, SL
core +1 more source
Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine [PDF]
KAE609 represents a new class of potent, fast-acting, schizonticidal antimalarials. This study investigated the safety and pharmacokinetics of KAE609 in combination with the long-acting antimalarial piperaquine (PPQ) in healthy volunteers.
Griffin, Paul +6 more
core +1 more source
Modelling the effects of disopyramide on short QT syndrome variant 1 in the human ventricles [PDF]
The short QT syndrome (SQTS) is a recently identified genetic disorder associated with ventricular and/or atrial arrhythmias and increased risk of sudden cardiac death.
Whittaker, DG +4 more
core +4 more sources
Corrected QT interval and QT dispersion in temporal lobe epilepsy [PDF]
Abstract Background Cardiac arrhythmias are expected among patients with epilepsy due to the effect of anti-epileptic drugs. Temporal lobe epilepsy also causes autonomic seizures that may affect heart rhythm. Prolongation of the corrected QT interval and QT dispersion is a risk factor for cardiac arrhythmia.
Maram Samy Nasef +5 more
openaire +2 more sources
The QT Intervals in Infancy and Time for Infantile ECG Screening for Long QT Syndrome [PDF]
Background: Electrocardiographic and molecular studies have clarified an association between sudden infant death syndrome (SIDS) and long QT syndrome (LQTS), and few data are available for the QT interval in infancy from birth to 1 year of age ...
Yoshinaga, Masao +13 more
core +2 more sources
QT peak prolongation predicts cardiac death following stroke [PDF]
Cardiac death has been linked in many populations to prolongation of the QT interval (QTe). However, basic science research suggested that the best estimate of the time point when repolarisation begins is near the T-wave peak.
Douglas, Denise +7 more
core +1 more source

