Results 41 to 50 of about 52,799 (238)
Arthritis &Rheumatology, EarlyView.Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu +12 more
wiley +1 more source
Calabi-Yau mirror symmetry as a gauge theory duality [PDF]
, 1999 Using brane set-ups we construct dual gauge theories in two dimensions with calN = (2,2) supersymmetry. Two different dualities are realized. One is basically a consequence of three-dimensional mirror symmetry. The nonlinear sigma model with a Calabi-Yau
Aganagic, Mina, Karch, Andreas
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh +5 more
wiley +1 more source
Electrocardiogram alterations following one-week consumption of Crocus sativus L. (saffron) [PDF]
, 2012 Considering the global popularity and also the various biological and medicinal properties of saffron, this study was conducted to assess the influence of its aqueous extracts administration on blood pressure, pressure-rate product (PRP) and ...
Joukar, Siyavash
core
British Journal of Clinical Pharmacology, EarlyView.Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert +6 more
wiley +1 more source
Possible predicative role of electrical risk score on transcatheter aortic valve replacement outcomes in older patients. preliminary data [PDF]
, 2018 Background:Transcatheter aortic valve replacement (TAVR) is an effective procedure capable to change the natural history of the degenerative aortic valve stenosis.
DI IORIO, Claudia +9 more
core +1 more source
Release of multicomponent pheromones from porous fibres
The Canadian Journal of Chemical Engineering, EarlyView.Abstract Surface engineering empowers a polymer exclusion net to serve dual functions: physical exclusion and pheromonal release, allowing for pest control in agricultural crops. In previous work, a net woven from porous fibres releasing simple, single‐component alarm pheromones showed promising results in field tests.
Darius Klassen +7 more
wiley +1 more source
Functional data analytic approach of modeling ECG T-wave shape to measure cardiovascular behavior
, 2010 The T-wave of an electrocardiogram (ECG) represents the ventricular repolarization that is critical in restoration of the heart muscle to a pre-contractile state prior to the next beat.
Sedransk, Nell, Zhou, Yingchun
core +1 more source
Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency
Epilepsia, EarlyView.Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon +9 more
wiley +1 more source
Correction: Utility of Corrected QT Interval in Orthostatic Intolerance
PLOS ONE, 2015 [This corrects the article DOI: 10.1371/journal.pone.0106417.].
openaire +3 more sources