Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Correction to "Understanding Medicaid Estate Recovery: The Experience of North Carolina and Policy Implications for Future Reforms". [PDF]
europepmc +1 more source
Correction: Intermittent upper limb cyanosis revealing Paget-Schroetter syndrome: the value of patient-provided photographs. [PDF]
Desjardins M +5 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Free-Breathing Arterial Spin Labeling MRI of the Kidney Using Flow-Sensitive-Alternating Inversion Recovery With Golden-Angle Radial Sampling. [PDF]
Zhang Y +10 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Correction to "Development, Suitability and Comprehensibility of a QR Code-Enabled Educational Package to Improve Self-Care Practices Among Patients With Type 2 Diabetes: A Multimethod Study in Iran". [PDF]
europepmc +1 more source

