Results 61 to 70 of about 357,319 (266)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Therapeutic Effectiveness of Postural Treatment on Youth Swimmers’ Anterior Shoulder Pain—An Interventional Study

Applied Sciences
The aim of our study was to investigate the effects of a 24-week-long training program on changes in static body posture, as well as the characteristics of anterior shoulder pain in youth swimmers, and the relationship between changes in whole-body ...
Dorottya Szabó, Gabriella Kiss, Eva Tékus, Petra Mayer, Márk Váczi, Judit Diana Fekete, Gergely Novográdecz, István Lázár, Katalin Gocze, Csaba Vermes, Tibor Mintál   +10 more
doaj   +1 more source

THE ROLE OF KINESITHERAPY AS PREVENTION AND MOTOR CONTROL OF POSTURAL DISORDERS IN ADOLESCENTS [PDF]

Journal of IMAB
Postural disorders are among the most common musculoskeletal problems of adolescents, which adversely affect their physical and mental development. The purpose of the study is to conduct a screening for the detection of postural disorders and determine ...
Petya Kasnakova, Biyanka Tornyova, Tanya Paskaleva   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Design of current signal frequency detecting device based on harmonic separation

Dianzi Jishu Yingyong, 2019
The frequency detection of current and voltage plays a very important role in the grid-connected control strategy. Large detection errors can cause failure of control algorithms such as phase lock, harmonic compensation and reactive power compensation ...
Han Xuelong, Hou Yinyin, Gu Nenghua, Han Shuangxia   +3 more
doaj   +1 more source

Implementation Personality Development Programs as a Mechanism of Social Control in Correctional Institutions

Jurnal Pendidikan Sosiologi dan Humaniora
This study aims to analyze the implementation of the personality development program as a social control mechanism in the Sungai Raya Class II Special Child Development Institution, which includes three main aspects, namely, planning, implementation, and program implementation results.
Echa Rahmayanti, Imran Imran, Fauziah Sri Wahyuni, Amrazi Zakso, Adhalia Zatalini   +4 more
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Substantiation of the developed program of physical rehabilitation of physically prepared persons with essential arterial hypertension of the I degree

Слобожанський науково-спортивний вісник, 2017
Purpose: scientifically substantiate the developed complex physical rehabilitation program aimed at accelerating the recovery process at different rehabilitation periods for people with essential hypertension of the first and second adulthood who have ...
Tamara Ridkovets, National University of Physical Education and Sports of Ukraine   +1 more
doaj   +1 more source

Efficacy of a program in increasing coping strategies in firefighters: randomized clinical trial [PDF]

Revista Latino-Americana de Enfermagem
Objective: to evaluate the effectiveness of a program in increasing coping strategies focused on military firefighters’ problems and emotions. Method: randomized, parallel, single-masked clinical trial.
Marli Aparecida Reis Coimbra, Érica Midori Ikegami, Lara Andrade Souza, Vanderlei José Haas, Maria Helena Barbosa, Lúcia Aparecida Ferreira   +5 more
doaj   +1 more source