Results 71 to 80 of about 78,461 (306)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Peran Kelembagaan Kantor Wilayah Kementerian Hukum dan HAM Dalam Upaya Optimalisasi Fungsi Lembaga Pemasyarakatan

open access: yesNagari Law Review
The aim of this research is to find out more about the institutional role of the Regional Office of the Ministry of Law and Human Rights in efforts to optimize the performance and implementation of the main functions of correctional institutions.
Janpatar Simamora, Putri Desima Pardede
doaj   +1 more source

FAIR INMATE COACHING PATTERNS (A STUDY IN CORRECTIONAL INSTITUTION OF KEDUNGPANE SEMARANG)

open access: yesJurnal Pembaharuan Hukum, 2020
Correctional Institutions have a very strategic task as the most potential place in realizing the objectives of punishment with coaching. However, this cannot be realized without the awareness of the inmates themselves.
achmad sulchan   +2 more
doaj   +1 more source

Redemption from the Inside-Out: The Power of Faith-Based Programming [PDF]

open access: yes, 2012
Prisons are tense, cheerless, and often degrading places in which all inmates struggle to maintain their equilibrium despite violence, exploitation, lack of privacy, stringent limitations on family and community contacts, and a paucity of opportunities ...
Jones, Richard S., Zaitzow, Barbara H.
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The Role of Correction Guardians In The Development of Private In Class I Surabaya Criminal Institutions

open access: yesYurisdiksi: Jurnal Wacana Hukum dan Sains
Sanctions for criminal acts committed. The role of correctional guardians is needed in the process of fostering Correctional Families who are the target of coaching carried out in Correctional Institutions.
Agung Wibowo Darmawan   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Spiral of Risk: Health Care Provision to Incarcerated Women [PDF]

open access: yes, 2006
By law, prisoners in the United States have a fundamental right to receive adequate health care. However, most prisoners in this nation face numerous obstacles when attempting to receive quality health services.

core  

Correction: Animal Welfare Institute [PDF]

open access: yesNature, 1990
A SENTENCE in the 30 August article on US animal regulations entitled "One step for-ward . . ." (Nature 346, 782; 1990) in-correctly paraphrased William Cotreau of the Animal Welfare Institute on the fre-quency of inspections of dog dealers. Federal officials were unable to inspect one-quarter of all dog dealers in 1988, not three-quarters, as the ...
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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