Results 121 to 130 of about 198,072 (320)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018 Background and Objectives: The elderly individuals undergoing hemodialysis have lower quality of life compared to their healthy counterparts due to the complications associated with treatment and sedentary lifestyle.
Mehrdad Bastani +2 more
doaj
Written and Oral Corrective Feedback in Task-Based Writing: A Case Study of Puyang Middle School [PDF]
, 2023 Jia Gou
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Physical Treatments, 2019 Purpose: This study aimed to evaluate the effects of a selected course of the core stabilization of body and hopping exercises on trunk strength and balance of female Kabaddi athletes.
Zohreh Torbatinezhad +2 more
doaj
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
His Corrective Pacing or Biventricular Pacing for Cardiac Resynchronization in Heart Failure.
Journal of the American College of Cardiology, 2019 G. Upadhyay +9 more
semanticscholar +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019 Introduction: Lifestyle and the constant use of communication technologies have led to the upper crossed syndrome. The purpose of this study was to investigate of the effect of comprehensive corrective exercises carried out in water on pain, neck flexors
Hossien Ahmadi +2 more
doaj