Results 131 to 140 of about 624,937 (366)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Can Corrective Ad Statements Based on \u3cem\u3eU.S. v. Philip Morris USA Inc.\u3c/em\u3e Affect Consumer Beliefs about Smoking? [PDF]
, 2010 To comply with the court\u27s ruling in U.S. v. Philip Morris USA Inc., tobacco companies must fund a large advertising campaign to \u27correct\u27 smoking beliefs about which consumers may have been misled as a result of past deceptive practices of ...
Andrews, J. Craig +3 more
core +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Corrective receding horizon EV charge scheduling using short-term solar forecasting [PDF]
, 2019 Forecast errors can cause sub-optimal solutions in resource planning optimization, yet they are usually modeled simplistically by statistical models, causing unrealistic impacts on the optimal solutions.
Haghi, HV +3 more
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Electrical noise reduction techniques contributing to improved data quality at the National Transonic Facility [PDF]
In initial use, the high-speed digital data acquisition systems at Langley Research Center's National Transonic Facility produced data containing unacceptably high noise levels.
Mcphee, J. R.
core +1 more source
Report of the State Budget Crisis Task Force: Final Report [PDF]
, 2014 The objective of the State Budget Task Force is to inform the public of the character and gravity of the fiscal issues confronting the states and the consequences of deferring corrective actions.
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