Results 131 to 140 of about 1,252,142 (297)

PERANCANGAN KONTEN e-LEARNING KEGIATAN CORRECTIVE MAINTENANCE MESIN EKSKAVATOR KOBELCO SK200 MENGGUNAKAN METODE SECI DAN ADDIE DI PO RAJAWALI PROJECT [PDF]

, 2019
PO Rajawali Project merupakan salah satu perusahaan yang bergerak di bidang penyewaan alat berat. Salah satu alat berat yang disewakan yaitu Ekskavator Kobelco SK200. Kobelco SK200 merupakan alat berat yang paling sering disewa oleh pelanggan.
MUHAMMAD ARIF \u27IZZUDIN
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Managed services for timely corrective maintenance in ABC Bank

, 2023
In this pandemic period, a pleasant physical work environment contributes to the overall well-being of employees which enhances their efficiency and quality performance.
Aquino, Ma. Kathleen S.
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Periodical Maintenance Modelling and Optimisation Assuming Imperfect Preventive Maintenance and Perfect Corrective Maintenance

, 2021
I denna rapport modelleras en periodisk underhållsmodell baserat på antagandenakontinuerlig tillsyn,. ofullständigt förebyggande underhåll (FU) och perfektavhjälpande underhåll (AU) genom tre beslutsvariabler (I, N, Z). Modellen härledsinom ramen för en oändlig planeringshorisont där genomsnittskostnaden pertidsenhet modelleras.
Engvall Birr, Madeleine, Lansryd, Lisette   +1 more
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PRE-EMPTIVE OR CORRECTIVE MAINTENANCE -AN OPTIMAL DECISION MODEL

, 2020
Nowadays we depend on equipment that may fail at any moment. But some failures may cause such big damage, e.g. the fall of an aircraft, that it is essential a preemptive maintenance strategy.

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Application of AI-based Predictive Maintenance for Industrial Processes

Tehnički Glasnik
Modern industry is increasingly relying on digital technologies to optimize maintenance processes, reduce costs and ultimately increase productivity.
Marko Fabić
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Corrective Ad Valorem and Unit Taxes: A Welfare Comparison [PDF]

The ad valorem versus unit taxes debate has traditionally emphasized tax yield. For this criterion, ad valorem taxes outperform unit taxes in terms of welfare for a wide range of imperfect competition settings, including Dixit-Stiglitz monopolistic ...
Susanne Dröge, Philipp J. H. Schröder
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