Results 71 to 80 of about 1,202,217 (287)
Factors influencing restoration time in railways
Transportation Research Interdisciplinary PerspectivesRailway incidents undermine both punctuality and capacity. As traffic volumes increase, the frequency of these incidents is also expected to increase, driven by higher asset utilization, reduced time for maintenance, and further worsened by climate ...
Grace Mukunzi +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A literature review-based evaluation framework for maintenance strategy selection in heavy vehicles
Results in EngineeringEffective maintenance strategies are critical for ensuring operational reliability, minimizing downtime, and optimizing resource utilization in fleet-based industrial operations.
Malihe Goli +2 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Usulan Strategi Perawatan Mesin Breaker dan Mesin Hammermill di PT. P&P Bangkinang
Jurnal Teknik Industri: Jurnal Hasil Penelitian dan Karya Ilmiah dalam Bidang Teknik Industri, 2017 PT. P & P Bangkinang merupakan sebuah perusahaan yang bergerak dalam pengolahan karet PT. P & P Bangkinang merupakan sebuah perusahaan yang bergerak dalam pengolahan karet mentah menjadi barang setengah jadi (Crumb Rubber) yang diekspor keluar negeri ...
wresni anggraini
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Optimisation of railway tamping scheduling
HeliyonThis research was devoted to optimising opportunistic tamping scheduling to present a cost-effective approach that considers both preventive and corrective tamping activities.
Mahdi Khosravi +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Rekayasa MesinTrains play a vital role in Indonesia's transportation system as they help reduce exhaust emissions and are one of the most environmentally friendly modes of transportation.
Oky Arfiansyah, I Gusti Nyoman Wiratmaja
doaj +1 more source