Results 181 to 190 of about 2,493,519 (340)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

PSAML: A Methodological Approach for Noninvasive Computerized Hydration Level Estimation. [PDF]

Sensors (Basel)
Liu X, Kang X, He L, Zhang J, Ting H, Yu X.   +5 more
europepmc   +1 more source

Ethics, Education, and \u27Political Correctness

, 1992
The term political correctness is itself a misnomer, a straw man (straw person?). Political correctness, at least on our campuses, has been defined by those opposed to and fearful of viewpoints they lump together under this loaded term.
Edelstein, Marilyn
core  

Learning and Motivation State Fluctuations from Motoric and Neurophysiologic Metrics during a Somatosensory Task in Mice. [PDF]

eNeuro
Bueno-Junior LS, Ghimire A, Ding M, Watson BO.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Japanese-Language AI Agent System for Human Papillomavirus Vaccine Infoveillance and Public Communication: Development and Feasibility Evaluation. [PDF]

JMIR Infodemiology
Liu J, Yang S, Ma D, Niu Q, Zhang Z, Nagai-Tanima M, Aoyama T.   +6 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

QbC: Quantum Correctness by Construction

Thanks to the rapid progress and growing complexity of quantum algorithms, correctness of quantum programs has become a major concern. Pioneering research over the past years has proposed various approaches to formally verify quantum programs using proof
Schaefer, Ina, Walter, Michael, Peduri, Anurudh   +2 more
core   +1 more source

Beef cattle industry stakeholder understanding of structural soundness: Opportunities for education. [PDF]

Transl Anim Sci
Greenwood MP, Murphrey TP, Briers G, Cleere J, Odom S.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source