Results 171 to 180 of about 22,234 (230)

The dynamics of transposable element content in the genome of the human pathogen Histoplasma. [PDF]

open access: yesFungal Genet Biol
Kurbessoian T   +9 more
europepmc   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi   +12 more
wiley   +1 more source

Integrating Machine Learning With Constant‐Potential Simulation to Unravel Charge‐Transfer Mechanisms in Electrochemical Nitrogen Fixation

open access: yesAdvanced Science, EarlyView.
Integrating interpretable machine learning with the fixed‐potential method reveals a novel mechanism: the catalytic activity of the electrochemical nitrogen reduction reaction is governed by partial charge transfer, induced by variations in the intermediate potential of zero charge under constant potential.
Yufei Xue   +6 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Gadolinium Nanoparticles: Emerging Platforms Beyond Imaging for Drug Delivery and Theranostics. [PDF]

open access: yesPharmaceutics
Shirazi AN   +5 more
europepmc   +1 more source

Enzyme‐Activated MRI for In Vivo Glucose Imaging via a Biodegradable Chromium Nanoprobe

open access: yesAdvanced Science, EarlyView.
Enzyme‐activated MRI (eaMRI) using a biodegradable CrGOx@Lip nanoprobe enables glucose‐specific imaging in vivo. GOx catalyzes glucose oxidation, triggering in situ formation of paramagnetic chromium gluconate and amplifying T1. This radiation‐free strategy maps tumor glucose uptake via the Warburg‐effect, quantifies hepatic glucose accumulation in ...
Yan Xu   +6 more
wiley   +1 more source

Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle

open access: yesAdvanced Science, EarlyView.
Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong   +7 more
wiley   +1 more source

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