Results 111 to 120 of about 6,729,386 (312)

Challenges and support needs among persons with a migration background who use drugs in four European metropolitan cities

open access: yesHarm Reduction Journal
Background Persons who migrate for economic reasons, along with asylum seekers and refugees, face multiple personal experiences and societal inequalities that increase the risk of mental health problems and substance dependency, compounded by ...
Aline Pouille   +9 more
doaj   +1 more source

A note on positive semi-definiteness of some non-pearsonian correlation matrices [PDF]

open access: yes
The Pearsonian coefficient of correlation as a measure of association between two variates is highly prone to the deleterious effects of outlier observations (in data).
Mishra, SK
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Panel regression analysis of the relationship between health resources and infant mortality rate in Chinese mainland provinces, 2010–2020

open access: yesFrontiers in Public Health
BackgroundChina has substantially reduced its infant mortality rate (IMR) and targets further declines under the Healthy China 2030 blueprint. Health resources are fundamental to infant health.
Ruonan Gao   +24 more
doaj   +1 more source

Tetrachoric Correlation as a Measure of default Correlation

open access: yesProcedia - Social and Behavioral Sciences, 2012
AbstractDefault correlation is a crucial in risk management. The aim of this paper is to introduce a new method for measuring default correlation. In this paper we recall tetrachoric correlation coefficient which is a measure of association between two continuous variables that have each been measured on a dichotomous scale.
Noyan Tekeli, Fatma   +1 more
openaire   +2 more sources

Structural Conditional Correlation [PDF]

open access: yes
A small strand of recent literature is occupied with identifying simultaneity in multiple equation systems through autoregressive conditional heteroscedasticity.
Weber, Enzo
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Mapping the applications and methodological characteristics of the TreeScan method in pharmacovigilance and beyond: a scoping review of 44 studies

open access: yesFrontiers in Pharmacology
BackgroundThe TreeScan method is an emerging tool for active safety signal surveillance and has been increasingly applied in post-marketing monitoring of pharmaceuticals and vaccines.ObjectiveTo evaluate methodological developments and application ...
Hailong Li   +43 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Advances on cancer vaccine trials registered in China and the USA in 2014-2024

open access: yesFrontiers in Oncology
ObjectiveThe clinical trials of cancer vaccine in China and the USA were summarized and compared over the past decade, thus putting forward suggestions for future clinical development in this field.MethodsMainly based on the Centre for Drug Evaluation of
Wei Shi   +17 more
doaj   +1 more source

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