A Meta-Analysis of Intracortical Device Stiffness and Its Correlation with Histological Outcomes [PDF]
, 2018 Allison M. Stiller +6 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Genotype–covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model [PDF]
, 2019 Guiyan Ni +5 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Joint contributions of cortical morphometry and white matter microstructure in healthy brain aging: A partial least squares correlation analysis [PDF]
, 2019 David A. Hoagey +3 more
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Experimental hierarchy and optimal robustness of quantum correlations of two-qubit states with controllable white noise [PDF]
, 2021 Kateřina Jiráková +4 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A correlation between the intrinsic brightness and average decay rate of Swift/UVOT gamma-ray burst optical/ultraviolet light curves [PDF]
, 2012 S. R. Oates +7 more
openalex +1 more source