Editorial: Low-dimensional structures, nanoparticles, and optical measurements
Claudia Yu. Zenkova +5 more
doaj +1 more source
Advances on cancer vaccine trials registered in China and the USA in 2014-2024
ObjectiveThe clinical trials of cancer vaccine in China and the USA were summarized and compared over the past decade, thus putting forward suggestions for future clinical development in this field.MethodsMainly based on the Centre for Drug Evaluation of
Wei Shi +17 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
M1 and M2 Macrophage Polarization Correlates with Activity and Chronicity Indices in Lupus Nephritis
Background: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), characterized by inflammation and immune dysregulation in the kidneys.
Chutima Chavanisakun +2 more
doaj +1 more source
The aim of the study was to investigate the phenotypic correlations and the regression curve among the main phenotypic parameters of milk yield in a herd of 63 primiparous Romanian Black Spotted breed dairy cows from SC Dorin&Sanda SRL, Petreşti-Alba ...
ELEONORA NISTOR, GH. NISTOR, V. BAMPIDIS
doaj
From the tower to the pews: A call for academic theology to re-engage with the local context
This article assesses the shortcomings and the disconnectedness of the current academic theological education in South Africa. It offers a brief history to provide a guiding principle for academic theology. It then proceeds to show the current disconnect
Jonathan M. Womack, Jerry Pillay
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Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Correlation between aneuploidy, standard morphology evaluation and morphokinetic development in 1730 biopsied blastocysts: a consecutive case series study [PDF]
Maria Giulia Minasi +9 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

