Results 131 to 140 of about 27,158,844 (263)

Econometric Analysis of Realised Covariation: High Frequency Covariance, Regression and Correlation in Financial Economics [PDF]

open access: yes
This paper analyses multivariate high frequency financial data using realised covariation. We provide a new asymptotic distribution theory for standard methods such as regression, correlation analysis and covariance.
Neil Shephard, Ole E. Barndorff-Nielsen
core  

Lung-Gut Microbiota and Tryptophan Metabolites Changes in Neonatal Acute Respiratory Distress Syndrome

open access: yesJournal of Inflammation Research
Jingli Yang,1– 4 Yu He,1– 5 Qing Ai,1– 4 Chan Liu,1– 4 Qiqi Ruan,1– 4 Yuan Shi1– 4 1Department of Neonatology, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2National Clinical Research Center for Child Health
Yang J, He Y, Ai Q, Liu C, Ruan Q, Shi Y
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Analysis of Body Mass Index and Clinicopathological Factors in Patients with Papillary Thyroid Carcinoma

open access: yesDiabetes, Metabolic Syndrome and Obesity
Wei Yan,1 Xue Luo,1 Qing-Jun Gao,1 Bing-Feng Chen,2 Hui Ye1 1Department of Thyroid Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, People’s Republic of China; 2Guizhou Medical University, Guiyang, 550001, People’s Republic of
Yan W, Luo X, Gao QJ, Chen BF, Ye H
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DeSTRESS Film 17: Turnover and Correlation

open access: yes, 2012
DeSTRESS films combine live-action explanation and interviews, filmed in a variety of locations, with narrated animations that take the viewer through a worked example. This film looks at why some firms grow very large while others stay small, discussing
destress project
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

AN EXHAUSTIVE COEFFICIENT OF RANK CORRELATION [PDF]

open access: yes
Rank association is a fundamental tool for expressing dependence in cases in which data are arranged in order. Measures of rank correlation have been accumulated in several contexts for more than a century and we were able to cite more than thirty of ...
Rosetta Lombardo, Agostino Tarsitano
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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