Results 71 to 80 of about 477,356 (259)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Detection Aided Multi-Filter Target Tracking Algorithm
IEEE Access, 2019 When the target is partially occluded or undergoes drastic appearance change, drift is prone to occur in traditional correlation filter-based trackers and ultimately leads to tracking failure. This paper proposes a robust tracking algorithm, which can be
Yue Min, Zhenzhong Wei, Ke Tan
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Wide-Area Search Tracking for Siamese Region Proposal Network
IEEE Access, 2020 With the introduction of deep learning technology into the field of visual tracking, the accuracy and robustness of visual tracking have greatly improved.
Hongwei Zhang +3 more
doaj +1 more source
Performance of Correlation Filters in Facial Recognition [PDF]
, 2011 In this paper, we compare the performance of three composite correlation filters in facial recognition problem. We used the ORL (Olivetti Research Laboratory) facial image database to evaluate K-Law, MACE and ASEF filters performance. Simulations results demonstrate that K-Law nonlinear composite filters evidence the best performance in terms of ...
Everardo Santiago-Ramírez +2 more
openaire +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Dual Model Learning Combined With Multiple Feature Selection for Accurate Visual Tracking
IEEE Access, 2019 Over these years, object tracking algorithms combined with correlation filters and convolutional features have achieved excellent performance in accuracy and real-time speed.
Jianming Zhang +4 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
PPIGCF: A Protein-Protein Interaction-Based Gene Correlation Filter for Optimal Gene Selection. [PDF]
Genes (Basel), 2023 Pati SK +4 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source