Results 111 to 120 of about 515 (205)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
ANTI-CORRELATIONISM CLUSTER AND PERFORMATIVE NARRATIVE
PHILOSOPHY, ECONOMICS AND LAW REVIEW, 2021 openaire +2 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Seria a psicanálise um correlacionismo?
Correlationism is a diagnostic category proposed by Meillassoux to characterize the current state of modern and contemporary continental philosophy. According to the author, every form of correlationism upholds the minimal thesis that the correlation ...
Antônio Teixeira, Bernardo Sollar Godoi
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
The purpose of the article is a comparative analysis of two strategies for overcoming correlationism. K. Meillassoux’s term captures the inextricable link between thinking and being in Modern European philosophy.
Valerii A. Moskvitin
core +1 more source
Translated into Japanese by Yuto Kannari from: “Transcendental Idealism and Strong Correlationism: Meillassoux and the End of Heideggerian Finitude,” by Jussi Backman, in Phenomenology and the Transcendental, edited by Sara Heinämaa, Mirja Hartimo, and ...
Backman, Jussi
core +2 more sources