Results 41 to 50 of about 4,147,721 (229)

Intervention and Statebuilding beyond the Human: From the ‘Black Box’ to the ‘Great Outdoors’ [PDF]

open access: yes, 2018
This article analyses intervention and statebuilding as shifting towards a posthuman discursive regime. It seeks to explore how the shift to ‘bottom-up’ or post-liberal approaches has evolved into a focus upon epistemological barriers to intervention and
Chandler, D., Chandler, D.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Encountering worlds: performance in/as philosophy in the ecological age [PDF]

open access: yes, 2015
This is an open access article that is freely available in ORE or from the publisher's web site.Within the context of the ‘Anthropocene’, the current geological epoch marked by the impact of human activity on terrestrial ecosystems and geological ...
Florencio, Joao
core   +4 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Learning Spatially Regularized Correlation Filters for Visual Tracking [PDF]

open access: yesIEEE International Conference on Computer Vision, 2015
Robust and accurate visual tracking is one of the most challenging computer vision problems. Due to the inherent lack of training data, a robust approach for constructing a target appearance model is crucial.
Martin Danelljan   +3 more
semanticscholar   +1 more source

Against the Virtual: Kleinherenbrink’s Externality Thesis and Deleuze’s Machine Ontology [PDF]

open access: yes, 2020
Drawing from Arjen Kleinherenbrink's recent book, Against Continuity: Gilles Deleuze's Speculative Realism (2019), this paper undertakes a detailed review of Kleinherenbrink's fourfold "externality thesis" vis-à-vis Deleuze's machine ontology.
Erkan, Ekin
core   +1 more source

The Oedipal Logic of Ecological Awareness [PDF]

open access: yes, 2012
The Anthropocene is the radical intersection of human history and geological time. Humans have belatedly realised that they have become a geophysical force on a planetary scale.
Morton, Timothy
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Speculative Realism: Resources on an Emerging Discipline [PDF]

open access: yes, 2010
Review of resources related to the "Speculative Realism" or "Object-Oriented Philosophy" movement that sprung up in the late ...
Eric Phetteplace
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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