Correlation Coefficients: Appropriate Use and Interpretation
Correlation in the broadest sense is a measure of an association between variables. In correlated data, the change in the magnitude of 1 variable is associated with a change in the magnitude of another variable, either in the same (positive correlation ...
P. Schober, C. Boer, L. Schwarte
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
User's guide to correlation coefficients
When writing a manuscript, we often use words such as perfect, strong, good or weak to name the strength of the relationship between variables. However, it is unclear where a good relationship turns into a strong one.
Haldun Akoglu
semanticscholar +1 more source
The law of becoming and the shackles of sufficient reason in Quentin Meillassoux [PDF]
Examining the concept of ‘hyper-chaos’ - a time beyond time, not of perpetual becoming, but of lawless creation and destruction, premised upon an abandonment of the principle of sufficient reason - as described in the work of French philosopher Quentin ...
Sutherland, Thomas
core
Close encounters of a critical kind: a diffractive musing in/between new material feminism and object-oriented ontology [PDF]
For a number of years, new material feminists have been developing new theoretical tools, new modes of conceptual analysis and new ethical frameworks.
Alaimo S. +33 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Repeated measures correlation (rmcorr) is a statistical technique for determining the common within-individual association for paired measures assessed on two or more occasions for multiple individuals.
J. Bakdash, L. Marusich
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
No TV for Woodpeckers by Gary Barwin, If Pressed by Andrew McEwan, and Ecology without Culture: Aesthetics for a Toxic World by Christine L. Marran [PDF]
Review of Gary Barwin\u27s No TV for Woodpeckers, Andrew McEwan\u27s If Pressed, and Christine L.
Sloane, Michael D
core +1 more source

