Results 71 to 80 of about 401 (212)

Synchronicity and Correlationism

open access: yes, 2012
The name of Carl Gustav Jung tends not to be associated with a concern for philosophical realism, seen, as he is, as one of the worst apologists for obscurantism, mysticism and spiritualism of the modern age. Yet the thesis I try to defend here is that Jung’s work can be read as an elaborate attempt to escape the “correlationist circle” and the impasse
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Speculative Materialism or Pragmatic Naturalism? Sellars contra Meillassoux [PDF]

open access: yes, 2017
Meillassoux's criticism of correlationism and the alternative he proposes are compared with Sellars's rationalistic pragmatism. I argue that Meillssoux's rejection of the principle of sufficient reason undermines the intelligibility of science itself ...
Sachs, Carl
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

On the Principles of Contradiction and Correlationism in the Wittgenstein’s Tractatus Logico-Philosophicus [PDF]

open access: yes, 2019
The article is devoted to the discussing the principle of contradiction in Tractatus Logico-Philosophicus. The author shows how this principle is violated only indirectly.
Kustov, S., Кустов, С. А.
core  

Deriving the Spiritual from the Material: A Speculatively Realist Perspective

open access: yesReligions
The existence of the spiritual can be deduced from knowledge of the material. There is an inherent affinity between speculation and spirituality: an embrace of gaps in knowledge.
Ian McLaughlin
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Before Infinitude: A Levinasian Response to Meillassoux’s Speculative Realism

open access: yes, 2017
This chapter argues that like Meillassoux, Levinas opposes correlationism—a term encompassing both idealism and anti-realism in philosophy. However, Levinas’s attempt to overcome correlationism differs markedly from that of Meillassoux.
Lee Braver
core   +1 more source

Expanding Speculative Realism & Speculative Materialism Meillassoux, and Correlationism [PDF]

open access: yes
This relationship between human and Cosmos, is what Meillassoux refers as “correlationism”. Humans can only establish a correlation with the world through representational structures, but never can they access the in itself.
Ajvazi, Irfan
core   +1 more source

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