Results 81 to 90 of about 401 (212)
AGI-Correlationism and Its Discontents
Információs TársadalomAnthropocentric and anthropomorphic biases and attitudes have been present inartificial intelligence (AI) research and practice since their beginning, being especiallynoticeable in artificial general intelligence. The aim of this paper is to proposea comprehensive framework for critical observation, as well as general theoreticalinquiry into these ...
openaire +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Introduction: Continental Realism – Picking Up the Pieces [PDF]
, 2017 This introductory chapter provides a historical overview of the emergence of new realist movements in contemporary continental philosophy, focusing in particular on speculative realism and materialism, object-oriented ontology, and transcendental ...
Marie-Eve Morin, Vladimir Dukić
core +1 more source
The Relational Materiality of Groundwater. [PDF]
GeoHumanities, 2021 Powis A.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
After Kant, Sellars, and Meillassoux: Back to Empirical Realism? [PDF]
, 2017 : I examine how Meillassoux’s conception of correlationism in After Finitude, as I understand it, relates firstly to Kant’s transcendental idealist philosophy, and secondly to the analytic Kantianism of Wilfrid Sellars. I argue that central to the views
O'Shea, James
core +2 more sources
Data’s Intimacy: Machinic Sensibility and the Quantified Self
communication +1, 2016 Today, machines observe, record the world – not just for us, but sometimes instead of us (in our stead), and even indifferently to us humans. And yet, remain human.
doaj +1 more source