Results 111 to 120 of about 2,266,709 (311)

On the Free-Surface Roughness in Incremental Forming of a Sheet Metal: A Study from the Perspective of ISF Strain, Surface Morphology, Post-Forming Properties, and Process Conditions

Metals, 2019
Due to absence of any supporting die, the free surfaces in incremental sheet forming (ISF) experience uneven deformation. This results in rough surfaces, possibly leading to the reduced service life of components.
Khalid A Al-Ghamdi, G. Hussain
doaj   +1 more source

On the Sampling Variance of Intraclass Correlations and Genetic Correlations [PDF]

Genetics, 1998
Abstract Widely used standard expressions for the sampling variance of intraclass correlations and genetic correlation coefficients were reviewed for small and large sample sizes. For the sampling variance of the intraclass correlation, it was shown by simulation that the commonly used expression, derived using a first-order Taylor ...
openaire   +5 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Lattice-commensurate skyrmion texture in a centrosymmetric breathing kagome magnet

npj Quantum Materials
Skyrmion lattices (SkL) in centrosymmetric materials typically have a magnetic period on the nanometer-scale, so that the coupling between magnetic superstructures and the underlying crystal lattice cannot be neglected. We reveal the commensurate locking
Max Hirschberger, Bertalan G. Szigeti, Mamoun Hemmida, Moritz M. Hirschmann, Sebastian Esser, Hiroyuki Ohsumi, Yoshikazu Tanaka, Leonie Spitz, Shang Gao, Kamil K. Kolincio, Hajime Sagayama, Hironori Nakao, Yuichi Yamasaki, László Forró, Hans-Albrecht Krug von Nidda, Istvan Kezsmarki, Taka-hisa Arima, Yoshinori Tokura   +17 more
doaj   +1 more source

Advancements in Data Analysis for the Work-Sampling Method

Algorithms
The work-sampling method makes it possible to gain valuable insights into what is happening in production systems. Work sampling is a process used to estimate the proportion of shift time that workers (or machines) spend on different activities (within ...
Borut Buchmeister, Natasa Vujica Herzog
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Reducing the biases of the conventional meta-analysis of correlations

Conventional meta-analyses (both fixed and random effects) of correlations are biased due to the correlation between the estimated correlation and its standard error. Simulations that are closely calibrated to match actual research conditions widely seen
T D Stanley, Tomas Havranek, Chris Doucouliagos   +2 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Dynamic Conditional Correlations in International Stock, Bond and Foreign Exchange Markets: Emerging Markets Evidence [PDF]

The paper models the dynamic conditional correlations in emerging stock, bond and foreign exchange markets using the DCC model of Engle (2002) and the GARCC model of McAleer et al. (2008).
Michael McAleer, Abdul Hakim
core