Results 131 to 140 of about 2,266,709 (311)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Factor-Spline-GARCH Model for High and Low Frequency Correlations [PDF]

open access: yes
We propose a new approach to model high and low frequency components of equity correlations. Our framework combines a factor asset pricing structure with other specifications capturing dynamic properties of volatilities and covariances between a single ...
Robert F. Engle, Jose Gonzalo Rangel
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Time Correlations Of Pressure In Isotropic Turbulence

open access: yes, 2008
The time correlations of pressure modes in stationary isotropic turbulence are investigated under the Kraichnan and Tennekes "random sweeping" hypothesis. A simple model is obtained which predicts a universal form for the time correlations.
Wang M   +4 more
core   +1 more source

Correlation concern

open access: yesJournal of Economic Theory
In many choice problems, the interaction between several distinct variables determines the payoff of each alternative. I propose and axiomatize a model of a decision maker who recognizes that she may not accurately perceive the correlation between these variables, and who takes this into account when making her decision.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Can fundamentals explain cross-country correlations of asset returns?. [PDF]

open access: yes
Previous studies show that existing correlations between national returns are higher than correlations between the national growth rates of fundamental variables.
Restoy, Fernando   +1 more
core  

Author Correction: Vital role of magnetocrystalline anisotropy in cubic chiral skyrmion hosts

open access: yesnpj Quantum Materials, 2021
M. Preißinger   +12 more
doaj   +1 more source

MILK PARAMETERS IN TERMS OF THE NEW BOOK OF REGULATIONS OF FRESH ROW MILK QUALITY [PDF]

open access: yesPoljoprivreda, 2001
Sanitary quality of milk and physical–chemical parameters became very important elements in evaluation and classification of milk in EU. Because of the market conditions and milk products position a new Book of Regulations of fresh raw milk quality came ...
P. Mijić   +6 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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