Results 181 to 190 of about 1,417,979 (268)

Through the Cultural Prism: The Influence of a Distinctive Chinese Personality-Junzi Personality-On Psychosocial Adjustment in China. [PDF]

Int J Psychol
Zhao B, Liu C, Muhetaer P, Hu P.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Individual differences in affect: explaining work environment perceptions and later wellbeing. [PDF]

Sci Rep
Craven LH, Kajonius PJ.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Meridian-sinew physical therapy modulates regional brain function and neurotransmitter spatial correlations in healthy volunteers: a neuroimaging study. [PDF]

Front Hum Neurosci
Zheng Y, Li K, Zhang G, Zheng H, Wu J, Zheng W.   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Estimation of Genetic Parameters of Body Weight and Body Size in Different Stages of Pishan Red Sheep. [PDF]

Animals (Basel)
Wujiwaili N, Huojiaabudula Y, Sataer B, Rouzimaimaiti A, Gong G, Qi A, Sulaiman Y.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Blood DNA methylation of EIF5A and TGIF1 is associated with adipose tissue health and metabolic outcomes in obesity: a multi-cohort study. [PDF]

Clin Epigenetics
Ruf S, Hoffmann A, Müller L, Landgraf K, Vogel M, Jørsboe E, Kubitz P, Dietrich A, Ghosh A, Noé F, Wolfrum C, Claussnitzer M, Hauner H, Stumvoll M, Baber R, Blüher M, Körner A, Kovacs P, Keller M.   +18 more
europepmc   +1 more source