Results 201 to 210 of about 2,266,709 (311)

Integrated Oral Microbiome and Metabolome Profiling Identifies Disease-Associated Multi-Omics Signatures in Alström and Bardet-Biedl Syndromes. [PDF]

Comput Struct Biotechnol J
Mojsak P, Zmyslowska-Polakowska E, Chmielewska S, Sołowiej K, Ploszaj T, Skoczylas S, Grzybowska-Adamowicz J, Pienkowski T, Kretowski A, Zmyslowska A, Ciborowski M.   +10 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Using ΦPSII and leaf temperature as indicators of non-steady-state photosynthesis and stomatal conductance during stepwise changes in light intensity. [PDF]

J Exp Bot
Javadi Asayesh E, Marcelis LFM, Acevedo-Siaca LG, Kaiser E.   +3 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Correction for Sireci et al., Environmental fluctuations explain the universal decay of species-abundance correlations with phylogenetic distance. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Quantitative Assessment of Anterior Segment OCT Parameters and Their Association with Intraocular Pressure in Primary Angle-Closure Disease. [PDF]

Diagnostics (Basel)
Gheorghe AG, Potop TG, Dascalescu DM, Marinescu MC, Dragosloveanu CD, Arghirescu AM, Rizea IM, Potop V.   +7 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Clinical Validity of Wrist- and Trunk-Worn Sensor-Derived Data Models in Parkinson's Disease. [PDF]

Parkinsons Dis
Sun Y, Day S, Walters K, Schrag A.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A preliminary analysis of the psychometric properties of the German O*NET interest profiler short form in rehabilitation education. [PDF]

Front Rehabil Sci
Wild S, Möhring M.
europepmc   +1 more source