Results 71 to 80 of about 1,504,306 (219)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Lattice-commensurate skyrmion texture in a centrosymmetric breathing kagome magnet

open access: yesnpj Quantum Materials
Skyrmion lattices (SkL) in centrosymmetric materials typically have a magnetic period on the nanometer-scale, so that the coupling between magnetic superstructures and the underlying crystal lattice cannot be neglected. We reveal the commensurate locking
Max Hirschberger   +17 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

RIXS observation of bond-directional excitations in the Kitaev material Na2IrO3

open access: yesnpj Quantum Materials
Spin-orbit coupling locks spin direction and spatial orientation and generates, in semi-classical magnets, a local spin easy-axis and associated ordering.
Marco Magnaterra   +15 more
doaj   +1 more source

Advancements in Data Analysis for the Work-Sampling Method

open access: yesAlgorithms
The work-sampling method makes it possible to gain valuable insights into what is happening in production systems. Work sampling is a process used to estimate the proportion of shift time that workers (or machines) spend on different activities (within ...
Borut Buchmeister, Natasa Vujica Herzog
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Tailoring of magnetism & electron transport of manganate thin films by controlling the Mn–O–Mn bond angles via strain engineering

open access: yesScientific Reports
Strain engineering beyond substrate limitation of colossal magnetoresistant thin (La0.6Pr0.4)0.7Ca0.3MnO3 (LPCMO) films on LaAlO3-buffered SrTiO3 (LAO/STO) substrates has been demonstrated using metalorganic aerosol deposition technique.
P. Henning   +8 more
doaj   +1 more source

A Systematic Review on Heat Transfer and Pressure Drop Correlations for Natural Refrigerants

open access: yesEnergies
Due to environmental concerns, natural refrigerants and their use in refrigeration and air conditioning systems are receiving more attention from manufacturers, end users and the scientific community.
Alberta Carella, Annunziata D’Orazio
doaj   +1 more source

Dependencies between some traits of sperm production of boars at different age [PDF]

open access: yesBiotechnology in Animal Husbandry, 2017
The aim of the study was to establish correlation and regression dependencies between some traits of sperm production of terminal boars (Large White x Pietrain). The analyzed material consisted of 347 ejaculates, received in the period from 2011 to 2014.
Zapryanova Ivelina
doaj  

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