Results 71 to 80 of about 3,917,551 (300)
We consider the following clustering problem: we have a complete graph on n vertices (items), where each edge (u, v) is labeled either + or – depending on whether u and v have been deemed to be similar or different. The goal is to produce a partition of the vertices (a clustering) that agrees as much as possible with the edge labels. That is, we want a
Bansal, N., Blum, A., Chawla, S.
openaire +3 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Towards minimal self-testing of qubit states and measurements in prepare-and-measure scenarios
Self-testing is a promising approach to certifying quantum states or measurements. Originally, it relied solely on the outcome statistics of the measurements involved in a device-independent (DI) setup.
Gábor Drótos +3 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Pressure-dependent magnetism of the Kitaev candidate Li2RhO3
We use magnetization measurements under pressure along with ab initio and cluster many-body calculations to investigate magnetism of the Kitaev candidate Li2RhO3.
Bin Shen +6 more
doaj +1 more source
Perfect correlations between noncommuting observables
The problem as to when two noncommuting observables are considered to have the same value arises commonly, but shows a nontrivial difficulty. Here, an answer is given by establishing the notion of perfect correlations between noncommuting observables ...
Braginsky +12 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Electronic correlations in organometallic complexes
We investigate an effective model for organometallic complexes (with potential uses in optoelectronic devices) via both exact diagonalisation and the configuration interaction singles (CIS) approximation.
A.C. Jacko +46 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

