Results 261 to 270 of about 5,341,246 (306)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

How Interviewees Determine What Interviewers Want to Know. [PDF]

Int Rev Soc Psychol
Neequaye DA, Lorson A, Barnett HK.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

MSAFusion: A Lightweight Multispectral Pedestrian Detection Network with Multi-Scale and Adaptive Feature Fusion. [PDF]

J Imaging
Song Y, Zuo X, Qu C, Qian Q, Jiang D.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Correspondence "Optimising the unilateral DIEP flap breast reconstruction: A United Kingdom-Netherlands multi-centre comparative study". [PDF]

JPRAS Open
Longo B, Vannucchi L, Giacalone M, D'Orsi G, Cervelli V.   +4 more
europepmc   +1 more source

RETRACTED ARTICLE: Optimizing sodium hydroxide concentration to enhance hydration and microstructure in limestone calcined clay cement (LC³). [PDF]

Sci Rep
Abbass AM, El-Khayatt AM.
europepmc   +1 more source

Correction for Cheng et al., "Simultaneous expression of three G genotypes of VP7 proteins in a recombinant porcine rotavirus confers protective immunity against multiple rotavirus infections". [PDF]

J Virol
Cheng X, Deng H, Bian X, Wang J, Wang C, Han N, Zhou J, Zhu X, Zhang X, Yang X, Tao R, Li B.   +11 more
europepmc   +1 more source

Reply to: Considerations of emerging diaphragmatic ultrasound techniques for clinical practice: potential pitfalls and future challenges. [PDF]

Eur Respir Rev
Neto Silva I, Bendjelid K.
europepmc   +1 more source

Correction to "Anxiety and Performance in High-Achieving Adolescents: Associations Among 8 General and Specific Anxiety Measures and 13 School Grades". [PDF]

Psych J
europepmc   +1 more source