Results 51 to 60 of about 4,802,781 (244)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Perceptions’ Real Representation in Sadra’s View; Examination and Explanation [PDF]
حکمت معاصر, 2013 It is generally conceived that the principal Mulla sadra’s approach in the problem of correspondence was to appeal to the prevalent foundationalism, and quiddity correspondence. However regarding the quiddity as a mere abstraction, as an element of Sadra’
Mohammad Nejati, Ahmad Beheshti
doaj
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Towards a Model for Encoding Correspondence in the TEI: Developing and Implementing
Journal of the Text Encoding Initiative, 2016 The encoding of letters has a long tradition in the TEI but there have been no official recommendations in the TEI Guidelines on how to deal with correspondence.
Peter Stadler +2 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Flaubert lecteur : une histoire des écritures
Flaubert: Revue Critique et Génétique, 2009 Flaubert reads to write. During the 1845-1857 period in particular his literary readings perfect his training and provide him with his esthetics, in a game of confrontations.
Philippe Dufour
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
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Frédéric et Rosanette, février 48
Flaubert: Revue Critique et Génétique, 2017 At the end of the second part of L’Éducation sentimentale, when describing Frédéric and Rosanette’s evening, which ends in Rue Tronchet, "in the home prepared for the other one" ("dans le logement préparé pour l’autre"), the author also paints a picture ...
Paul Raucy
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source