Results 161 to 170 of about 6,402,656 (281)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Simultaneous Object and Category Score Estimation in Joint Correspondence Analysis. [PDF]

Psychometrika
Makino N.
europepmc   +1 more source

Assessment of improvement in anxiety severity for children with autism spectrum disorder: The matched correspondence analysis approach. [PDF]

J Psychiatr Res, 2022
Kim SK, McKay D, Cepeda SL, Schneider SC, Wood J, Storch EA.   +5 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Correspondence Analysis [PDF]

, 2008
  +5 more sources

Tracking the emergence of the Upper Palaeolithic in western Asia and Europe: A Multiple Correspondence Analysis of Protoaurignacian and Southern Ahmarian lithics. [PDF]

PLoS One
Gennai J, Falcucci A, Niochet V, Peresani M, Richter J, Soressi M.   +5 more
europepmc   +1 more source

Motivation Levels and Goals for the Practice of Physical Exercise in Five Different Modalities: A Correspondence Analysis. [PDF]

Front Psychol, 2021
Borges JC, de Oliveira Filho GG, de Lira CAB, da Silva RAD, Alves EDS, Benvenutti MJ, Rosa JPP.   +6 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Genome Data Exploration Using Correspondence Analysis

Bioinformatics and Biology Insights, 2016
Fredj Tekaia
doaj  

Investigating Associations Between Prognostic Factors in Gliomas: Unsupervised Multiple Correspondence Analysis. [PDF]

JMIR Bioinform Biotechnol
Goes Job ME, Fukumasu H, Malta TM, Porfirio Xavier PL.   +3 more
europepmc   +1 more source