Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Biplot and Singular Value Decomposition Macros for Excel© [PDF]
The biplot display is a graph of row and column markers obtained from data that forms a two-way table. The markers are calculated from the singular value decomposition of the data matrix.
Eric P. Smith, Ilya A. Lipkovich
core +1 more source
Educational patterns of health behaviors and body mass index: A longitudinal multiple correspondence analysis of a middle-aged general population, 2007-2016. [PDF]
PLoS One, 2023 Ibarra-Sanchez AS +3 more
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Contrastive multiple correspondence analysis (cMCA): Using contrastive learning to identify latent subgroups in political parties. [PDF]
PLoS One, 2023 Fujiwara T, Liu TP.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Exploring the association between self-efficacy and future utility beliefs in mathematics: A practical tutorial on correspondence analysis. [PDF]
PLoS One, 2023 Alzahrani A, Beh EJ, Stojanovski E.
europepmc +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell RNA-seq data. [PDF]
Sci Rep, 2023 Hsu LL, Culhane AC.
europepmc +1 more source