Evidence for corrin biosynthesis in the last universal common ancestor. [PDF]
FEBS JCobalamin biosynthesis can be traced back to the last universal common ancestor. After a stage of chemical evolution of the acetyl‐CoA pathway, the enzymatic synthesis of cobalamin evolved, allowing life to be independent of the insoluble solid‐state catalysts that tethered primordial CO2 assimilation to the Earth's crust, suggesting a role for corrin ...
Modjewski LD +5 more
europepmc +2 more sources
Soil microbial community response to corrinoids is shaped by a natural reservoir of vitamin B12. [PDF]
ISME JSoil microbial communities perform critical ecosystem services through the collective metabolic activities of numerous individual organisms. Most microbes use corrinoids, a structurally diverse family of cofactors related to vitamin B12.
Hallberg ZF +9 more
europepmc +3 more sources
Phylogenetic distribution and experimental characterization of corrinoid production and dependence in soil bacterial isolates. [PDF]
ISME JSoil microbial communities impact carbon sequestration and release, biogeochemical cycling, and agricultural yields. These global effects rely on metabolic interactions that modulate community composition and function.
Alvarez-Aponte ZI +10 more
europepmc +3 more sources
Laboratory evolution of <i>E. coli</i> with a natural vitamin B<sub>12</sub> analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth. [PDF]
J BacteriolBacteria encounter chemically similar nutrients in their environment, which impact their growth in distinct ways. Among such nutrients are cobamides, the structurally diverse family of cofactors related to vitamin B12 (cobalamin), which function as ...
Mok KC +3 more
europepmc +3 more sources
Nutrient cross-feeding in the microbial world. [PDF]
, 2014 The stability and function of a microbial community depends on nutritional interactions among community members such as the cross-feeding of essential small molecules synthesized by a subset of the population.
Seth, Erica C, Taga, Michiko E
core +2 more sources
Methylobacterium sp. 2A is a plant growth-promoting rhizobacteria that has the potential to improve potato crop yield under adverse conditions [PDF]
, 2020 A Gram-negative pink-pigmented bacillus (named 2A) was isolated from Solanum tuberosum L. cv. Desirée plants that were strikingly more developed, presented increased root hair density, and higher biomass than other potato lines of the same age.
Fantino, Elisa Inés +5 more
core +1 more source
Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme. [PDF]
, 2019 Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life.
Mok, Kenny +5 more
core +1 more source
Novel pathway for corrinoid compounds production in lactobacillus [PDF]
, 2018 Vitamin B12 or cobalamin is an essential metabolite for humans, which makes it an interesting compound for many research groups that focus in different producer-strains synthesis pathways.
Font, Graciela Maria +4 more
core +2 more sources
Mouse Transcobalamin Has Features Resembling both Human Transcobalamin and Haptocorrin [PDF]
, 2011 In humans, the cobalamin (Cbl) -binding protein transcobalamin (TC) transports Cbl from the intestine and into all the cells of the body, whereas the glycoprotein haptocorrin (HC), which is present in both blood and exocrine secretions, is able to bind ...
AL Morkbak +30 more
core +12 more sources
Resonance Raman optical activity spectroscopy in probing structural changes invisible to circular dichroism spectroscopy : a study on truncated vitamin $B_{12}$ derivatives [PDF]
, 2020 This work demonstrates resonance Raman optical activity (RROA) spectra of three truncated vitamin B12 derivatives modified within the nucleotide loop. Since truncated cobalamins possess sufficiently high rotational strength in the range of ROA excitation
Barańska, Małgorzata +5 more
core +1 more source