Resonance Raman Optical Activity Spectroscopy in Probing Structural Changes Invisible to Circular Dichroism Spectroscopy: A Study on Truncated Vitamin B12 Derivatives [PDF]
Molecules, 2020 This work demonstrates resonance Raman optical activity (RROA) spectra of three truncated vitamin B12 derivatives modified within the nucleotide loop. Since truncated cobalamins possess sufficiently high rotational strength in the range of ROA excitation
Ewa Machalska +5 more
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Genome-Based Metabolic Reconstruction Unravels the Key Role of B12 in Methionine Auxotrophy of an Ortho-Phenylphenol-Degrading Sphingomonas haloaromaticamans [PDF]
Frontiers in Microbiology, 2020 Auxotrophy to amino acids and vitamins is a common feature in the bacterial world shaping microbial communities through cross-feeding relations. The amino acid auxotrophy of pollutant-degrading bacteria could hamper their bioremediation potential ...
Chiara Perruchon +3 more
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Phylogenetic distribution and experimental characterization of corrinoid production and dependence in soil bacterial isolates. [PDF]
ISME JSoil microbial communities impact carbon sequestration and release, biogeochemical cycling, and agricultural yields. These global effects rely on metabolic interactions that modulate community composition and function.
Alvarez-Aponte ZI +10 more
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Evidence for corrin biosynthesis in the last universal common ancestor. [PDF]
FEBS JCobalamin biosynthesis can be traced back to the last universal common ancestor. After a stage of chemical evolution of the acetyl‐CoA pathway, the enzymatic synthesis of cobalamin evolved, allowing life to be independent of the insoluble solid‐state catalysts that tethered primordial CO2 assimilation to the Earth's crust, suggesting a role for corrin ...
Modjewski LD +5 more
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Nomenclature of Corrinoids [PDF]
Pure and Applied Chemistry, 1976 A Braunstein +35 more
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The prospects for the use of vitamin B12 derivatives in pharmacology
Фармакоэкономика, 2023 Background. The structure of corrin tetrapyrrole macrocycles (compounds similar in structure to vitamin B12) is a kind of universal chemical template for targeted drug delivery, and the development of chemical sensors and antidotes.Objective ...
I. Yu. Torshin +2 more
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Corrinoids in anaerobic bacteria [PDF]
FEMS Microbiology Letters, 1990 C1-metabolizing bacteria were analyzed for their corrinoids. The autotrophic phototrophe Chloroflexus aurantiacus contains predominantly the light-sensitive coenzyme B12. The corrinoid could be teh prostethic group of a methylmalonyl-CoA mutase, which is involved in the CO2 fixing reaction sequence from proplonyl-CoA to succinyl CoA.
Erhard Stupperich +2 more
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A vitamin B12 transporter in Mycobacterium tuberculosis [PDF]
Open Biology, 2013 Vitamin B12-dependent enzymes function in core biochemical pathways in Mycobacterium tuberculosis, an obligate pathogen whose metabolism in vivo is poorly understood. Although M.
Krishnamoorthy Gopinath +6 more
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Influence of corrinoid antagonists on methanogen metabolism [PDF]
Journal of Bacteriology, 1981 Iodopropane inhibited cell growth and methane production when Methanobacterium thermoautotrophicum, Methanobacterium formicicum, and Methanosarcina barkeri were cultured on H2-CO2. Iodopropane (40 microM) inhibited methanogenesis (30%) and growth (80%) when M. barkeri was cultured mixotrophically on H2-CO2-methanol.
William R. Kenealy, J. G. Zeikus
openalex +3 more sources
Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities [PDF]
Environmental Microbiology, 2014 Summary Cobalamin and other corrinoids are essential cofactors for many organisms. The majority of microbes with corrinoid‐dependent enzymes do not produce corrinoids de novo , and instead must acquire corrinoids produced by other organisms in their environment. However, the
Men, Yujie +6 more
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