Results 11 to 20 of about 3,260 (236)

Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins [PDF]

eLife, 2018
Human gut Bacteroides use surface-exposed lipoproteins to bind and metabolize complex polysaccharides. Although vitamins and other nutrients are also essential for commensal fitness, much less is known about how commensal bacteria compete with each other
Aaron G Wexler, Whitman B Schofield, Patrick H Degnan, Ewa Folta-Stogniew, Natasha A Barry, Andrew L Goodman   +5 more
doaj   +3 more sources

Evidence for corrin biosynthesis in the last universal common ancestor. [PDF]

FEBS J
Cobalamin biosynthesis can be traced back to the last universal common ancestor. After a stage of chemical evolution of the acetyl‐CoA pathway, the enzymatic synthesis of cobalamin evolved, allowing life to be independent of the insoluble solid‐state catalysts that tethered primordial CO2 assimilation to the Earth's crust, suggesting a role for corrin ...
Modjewski LD, Karavaeva V, Mrnjavac N, Knopp M, Martin WF, Sousa FL.   +5 more
europepmc   +2 more sources

Studies on the Corrinoids and Porphyrins in Streptomycetes

Agricultural and Biological Chemistry, 1968
A corrinoid, formed predominantly in the cells of Streptomyces olivaceus 605 grown aerobically on a glucose-lactose medium, was identical with 5,6-dimethylbenzimidazolyl-cobamide coenzyme (DBC coenzyme) by paper chromatography, paper ionophoresis, absorption spectrophotometry, assay of the coenzyme activity in diol dehydratase system and other tests ...
Kazuyoshi Sato, Shoichi Shimizu, Saburo Fukui   +2 more
  +9 more sources

Native Corrinoids fromClostridium cochleariumAre Adeninylcobamides: Spectroscopic Analysis and Identification of Pseudovitamin B₁₂and Factor A [PDF]

Journal of Bacteriology, 2000
The corrinoids from the obligate anaerobe Clostridium cochlearium were extracted as a mixture of Coβ-cyano derivatives. From 50 g of frozen cells, approximately 2 mg (1.5 μmol) of B12 derivatives was obtained as a crystalline sample.
Bernd Hoffmann, Michael Oberhuber, Erhard Stupperich, Harald Bothe, Wolfgang Buckel, Robert Konrat, Bernhard Kräutler   +6 more
openalex   +2 more sources

Corrinoids in anaerobic bacteria [PDF]

FEMS Microbiology Letters, 1990
C1-metabolizing bacteria were analyzed for their corrinoids. The autotrophic phototrophe Chloroflexus aurantiacus contains predominantly the light-sensitive coenzyme B12. The corrinoid could be teh prostethic group of a methylmalonyl-CoA mutase, which is
E. Stupperich, H. Eisinger, Sabine Schurr   +2 more
semanticscholar   +3 more sources

Phylogenetic distribution and experimental characterization of corrinoid production and dependence in soil bacterial isolates. [PDF]

ISME J
Soil microbial communities impact carbon sequestration and release, biogeochemical cycling, and agricultural yields. These global effects rely on metabolic interactions that modulate community composition and function.
Alvarez-Aponte ZI, Govindaraju AM, Hallberg ZF, Nicolas AM, Green MA, Mok KC, Fonseca-García C, Coleman-Derr D, Brodie EL, Carlson HK, Taga ME.   +10 more
europepmc   +3 more sources

Identification of a Novel Cobamide Remodeling Enzyme in the Beneficial Human Gut Bacterium Akkermansia muciniphila [PDF]

mBio, 2020
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A.
Kenny C. Mok, Olga M. Sokolovskaya, Alexa M. Nicolas, Zachary F. Hallberg, Adam Deutschbauer, Hans K. Carlson, Michiko E. Taga   +6 more
doaj   +2 more sources

Crystal structure of a methyltetrahydrofolate- and corrinoid-dependent methyltransferase [PDF]

Structure, 2000
Methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr), catalyzes a key step in the Wood-Ljungdahl pathway of carbon dioxide fixation. It transfers the N5-methyl group from methyltetrahydrofolate (CH3-H4folate) to a cob(I)amide center in another protein, the corrinoid iron-sulfur protein. MeTr is a member of a family of proteins
Tzanko Doukov, Javier Seravalli, John J. Stezowski, Stephen W. Ragsdale   +3 more
openalex   +4 more sources

Dihydroflavin-driven Adenosylation of 4-Coordinate Co(II) Corrinoids

Journal of Biological Chemistry, 2009
The identity of the source of the biological reductant needed to convert cobalamin to its biologically active form adenosylcobalamin has remained elusive.
Paola E. Mera, Jorge C. Escalante‐Semerena   +1 more
openalex   +2 more sources

A New Principle for Measurement of Cobalamin and Corrinoids, Used for Studies of Cobalamin Analogs on Serum Haptocorrin [PDF]

Clinical Chemistry, 2009
BACKGROUND Transcobalamin (TC) and haptocorrin (HC) are serum corrinoid-binding proteins. We developed new methods for measurement of the corrinoids bound to HC and TC.
Tore Forsingdal Hardlei, Ebba Nexø
openalex   +2 more sources