Investigating the origins of B12 biosynthesis in the most ancient roots of the tree of life [PDF]
Vitamin B12, also known as B12 or cobalamin, is a vital nutrient required across all branches of life, but the ability to synthesize this complex molecule de novo is limited to only a few archaea and bacteria.
Alicea, Edil +5 more
core
FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR) [PDF]
Adenosylcobalamin, the coenzyme form of vitamin B12, is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt
Alan Scott +45 more
core +3 more sources
Identification of abiotic and biotic reductive dechlorination in a chlorinated ethene plume after thermal source remediation by means of isotopic and molecular biology tools [PDF]
Thermal tetrachloroethene (PCE) remediation by steam injection in a sandy aquifer led to the release of dissolved organic carbon (DOC) from aquifer sediments resulting in more reduced redox conditions, accelerated PCE biodegradation, and changes in ...
Badin, Alice +5 more
core +2 more sources
Predicting the conformations of peptides and proteins in early evolution. A review article submitted to Biology Direct [PDF]
Considering that short, mainly heterochiral, polypeptides with a high glycine content are expected to have played a prominent role in evolution at the earliest stage of life before nucleic acids were available, we review recent knowledge about ...
Milner-White, E.J., Russell, M.
core +4 more sources
Measuring and tracking vitamin B12: a review of current methods with a focus on optical spectroscopy [PDF]
Published online: 13 Sep 2016Vitamin B12 deficiency has been associated with an increased risk of cognitive decline. This literature review explores the current methods available for measuring vitamin B12 in human blood, serum, and urine, and the need ...
Brooks, J. +3 more
core +1 more source
Microbial demethylation of dimethylsulfoniopropionate and methylthiopropionate [PDF]
As discussed in chapter 1 , there is an increased interest in the production of certain natural sulfur-containing flavor compounds or flavor precursors.
Jansen, Michael,
core +3 more sources
Acetylene Fuels TCE Reductive Dechlorination by Defined Dehalococcoides/Pelobacter Consortia. [PDF]
Acetylene (C2H2) can be generated in contaminated groundwater sites as a consequence of chemical degradation of trichloroethene (TCE) by in situ minerals, and C2H2 is known to inhibit bacterial dechlorination. In this study, we show that while high C2H2 (
Alvarez-Cohen, Lisa +6 more
core +2 more sources
A Mechanochemical Switch to Control Radical Intermediates [PDF]
B12-dependent enzymes employ radical species with exceptional prowess to catalyze some of the most chemically challenging, thermodynamically unfavorable reactions.
Brunk, Elizabeth +3 more
core +6 more sources
Unravelling the one-carbon metabolism of the acetogen Sporomusa strain An4 by genome and proteome analysis [PDF]
The Sporomusa genus comprises anaerobic spore-forming acetogenic bacteria that stain Gram-negative. Sporomusa species typically grow with one-carbon substrates and N-methylated compounds.
Altimira +69 more
core +1 more source
Is the Hyporheic Zone Relevant beyond the Scientific Community? [PDF]
Rivers are important ecosystems under continuous anthropogenic stresses. The hyporheic zone is a ubiquitous, reactive interface between the main channel and its surrounding sediments along the river network. We elaborate on the main physical, biological,
Arnon, Shai +9 more
core +1 more source

