Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]
, 2019 The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R +6 more
core +1 more source
Theoretical Modeling of Low-Energy Electronic Absorption Bands in Reduced Cobaloximes [PDF]
, 2014 The reduced Co^I states of cobaloximes are powerful nucleophiles that play an important role in the hydrogen-evolving catalytic activity of these species.
Arantes, Guilherme M. +9 more
core +4 more sources
FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR) [PDF]
, 2014 Adenosylcobalamin, the coenzyme form of vitamin B12, is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt
Alan Scott +45 more
core +3 more sources
Identification of abiotic and biotic reductive dechlorination in a chlorinated ethene plume after thermal source remediation by means of isotopic and molecular biology tools [PDF]
, 2016 Thermal tetrachloroethene (PCE) remediation by steam injection in a sandy aquifer led to the release of dissolved organic carbon (DOC) from aquifer sediments resulting in more reduced redox conditions, accelerated PCE biodegradation, and changes in ...
Badin, Alice +5 more
core +2 more sources
Investigating the origins of B12 biosynthesis in the most ancient roots of the tree of life [PDF]
, 2015 Vitamin B12, also known as B12 or cobalamin, is a vital nutrient required across all branches of life, but the ability to synthesize this complex molecule de novo is limited to only a few archaea and bacteria.
Alicea, Edil +5 more
core
Trace Metal Requirements for Microbial Enzymes Involved in the Production and Consumption of Methane and Nitrous Oxide [PDF]
, 2012 Fluxes of greenhouse gases to the atmosphere are heavily influenced by microbiological activity. Microbial enzymes involved in the production and consumption of greenhouse gases often contain metal cofactors.
Jennifer B. Glass, Victoria J. Orphan
core +2 more sources
Microbial demethylation of dimethylsulfoniopropionate and methylthiopropionate [PDF]
, 2000 As discussed in chapter 1 , there is an increased interest in the production of certain natural sulfur-containing flavor compounds or flavor precursors.
Jansen, Michael,
core +3 more sources
A Mechanochemical Switch to Control Radical Intermediates [PDF]
, 2014 B12-dependent enzymes employ radical species with exceptional prowess to catalyze some of the most chemically challenging, thermodynamically unfavorable reactions.
Brunk, Elizabeth +3 more
core +6 more sources
Measuring and tracking vitamin B12: a review of current methods with a focus on optical spectroscopy [PDF]
, 2017 Published online: 13 Sep 2016Vitamin B12 deficiency has been associated with an increased risk of cognitive decline. This literature review explores the current methods available for measuring vitamin B12 in human blood, serum, and urine, and the need ...
Brooks, J. +3 more
core +1 more source
Unravelling the one-carbon metabolism of the acetogen Sporomusa strain An4 by genome and proteome analysis [PDF]
, 2016 The Sporomusa genus comprises anaerobic spore-forming acetogenic bacteria that stain Gram-negative. Sporomusa species typically grow with one-carbon substrates and N-methylated compounds.
Altimira +69 more
core +1 more source