Results 41 to 50 of about 7,441 (174)
Oil and Vinegar: Modern Parameters and Implementations
Two multivariate digital signature schemes, Rainbow and GeMSS, made it into the third round of the NIST PQC competition. However, neither made its way to being a standard due to devastating attacks (in one case by Beullens, the other by Tao, Petzoldt ...
Ward Beullens +6 more
doaj +1 more source
The transition of cetaceans from a terrestrial to an aquatic environment involved a crucial sensory adaptation to environments with limited visibility. Vibrissae, important mechanoreceptors, undergo an ontogenetic transformation in odontocetes. This research describes the histomorphology of vibrissae and crypts at different developmental stages ...
Cecilia Mariana Krmpotic +10 more
wiley +1 more source
Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková +3 more
wiley +1 more source
Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley +1 more source
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
UV exposure induces cuticular and cortical damage in natural hair, with oxidative effects and protein degradation comparable to bleaching. However, double bleaching leads to significantly greater structural degradation, emphasizing distinct mechanisms and severity of chemical versus UV‐induced damage. Abstract The combination of chemist techniques is a
Nathana Cindy Barros Silva Ramos +7 more
wiley +1 more source
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer +4 more
wiley +1 more source
Optimized Falcon Verify on Cortex-M4 for Post-Quantum secure UAV communications
Falcon, a NIST-standardized DSA, is ideal for broadcast-based communication like UAV due to its short key and signature. Since each UAV broadcasts the signed message to surrounding parties, UAVs must verify numerous signatures in flight.
JunHyeok Choi +2 more
doaj +1 more source
Abstract Purpose The present study aimed to evaluate, in a preclinical setting, the biomechanical behavior and mechanical performance of a newly developed dental implant nut system designed to address primary stability challenges in the severely resorbed posterior maxilla.
Mert Şahin +4 more
wiley +1 more source
AuCPace: Efficient verifier-based PAKE protocol tailored for the IIoT
Increasingly connectivity becomes integrated in products and devices that previously operated in a stand-alone setting. This observation holds for many consumer applications in the so-called "Internet of Things" (IoT) as well as for corresponding ...
Björn Haase, Benoît Labrique
doaj +1 more source

