Results 71 to 80 of about 11,679 (206)

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Optimized Falcon Verify on Cortex-M4 for Post-Quantum secure UAV communications

ICT Express
Falcon, a NIST-standardized DSA, is ideal for broadcast-based communication like UAV due to its short key and signature. Since each UAV broadcasts the signed message to surrounding parties, UAVs must verify numerous signatures in flight.
JunHyeok Choi, SeungYong Yoon, Seog Chung Seo   +2 more
doaj   +1 more source

Task-Projected Hyperdimensional Computing for Multi-Task Learning

, 2020
Brain-inspired Hyperdimensional (HD) computing is an emerging technique for cognitive tasks in the field of low-power design. As a fast-learning and energy-efficient computational paradigm, HD computing has shown great success in many real-world ...
A Rahimi, M Imani, N Abbas, P Kanerva, RM French, SG Leem, TA Plate   +6 more
core   +1 more source

The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Alzheimer's disease (AD) and glioblastoma multiforme (GBM) are biologically distinct age‐related brain disorders with opposing clinical phenotypes. AD is characterised by progressive neurodegeneration and cognitive decline, whereas GBM is characterised by aggressive cellular proliferation and a poor prognosis.
Ana B. Caniceiro, Sofia P. Agostinho, Luiz F. Piochi, Nícia Rosário‐Ferreira, Irina S. Moreira   +4 more
wiley   +1 more source

AuCPace: Efficient verifier-based PAKE protocol tailored for the IIoT

Transactions on Cryptographic Hardware and Embedded Systems, 2019
Increasingly connectivity becomes integrated in products and devices that previously operated in a stand-alone setting. This observation holds for many consumer applications in the so-called "Internet of Things" (IoT) as well as for corresponding ...
Björn Haase, Benoît Labrique
doaj   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, Volume 13, Issue 17, 23 March 2026.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, Volume 7, Issue 3, March 2026.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Enabling PERK and other MPC-in-the-Head Signatures on Resource-Constrained Devices

Transactions on Cryptographic Hardware and Embedded Systems
One category of the digital signatures submitted to the NIST Post-Quantum Cryptography Standardization Process for Additional Digital Signature Schemes comprises proposals constructed leveraging the MPC-in-the-Head (MPCitH) paradigm.
Slim Bettaieb, Loïc Bidoux, Alessandro Budroni, Marco Palumbi, Lucas Pandolfo Perin   +4 more
doaj   +1 more source

Distribution of Muscarinic Acethylcholine Receptors and Related Signal [PDF]

Türk Biyokimya Dergisi, 2006
Muscarinic receptors are members of G protein coupled receptor family. Molecularcloning studies indicate five intronless genes that encode five muscarinic receptorglycoproteins.
Hülya Cabadak
doaj  

Unusual Synchronous Arbitrary‐Gate Doppler Spectra Enable Intraoperative Hemodynamic Warning of Cerebral Hyperperfusion Syndrome on Moyamoya Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Synchronous arbitrary‐gate spectral Doppler (SAGSD) enables real‐time multi‐site hemodynamic monitoring during moyamoya disease revascularization. The novel “mountain” sign, defined as three or more velocity peaks within one cardiac cycle across multiple subcortical sites, was detected in 5 of 6 patients who developed cerebral hyperperfusion syndrome ...
Xiandi Zhang, Wei Ni, Xing Hu, Heng Yang, Jiabin Su, Hanqiang Jiang, Chao Gao, Ruiyuan Weng, Zhen Fan, Yiming Li, Jinhua Yu, Zhaoling Lu, Yuxiang Gu, Hong Ding   +13 more
wiley   +1 more source