Results 51 to 60 of about 1,669,272 (363)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Integration of somatosensory and motor-related information in the auditory system

open access: yesFrontiers in Neuroscience, 2022
An ability to integrate information provided by different sensory modalities is a fundamental feature of neurons in many brain areas. Because visual and auditory inputs often originate from the same external object, which may be located some distance ...
Michael Lohse   +3 more
doaj   +1 more source

Rule learning enhances structural plasticity of long-range axons in frontal cortex. [PDF]

open access: yes, 2016
Rules encompass cue-action-outcome associations used to guide decisions and strategies in a specific context. Subregions of the frontal cortex including the orbitofrontal cortex (OFC) and dorsomedial prefrontal cortex (dmPFC) are implicated in rule ...
Johnson, Carolyn   +3 more
core   +3 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Dipicolinic Acid Release by Germinating Clostridium difficile Spores Occurs through a Mechanosensing Mechanism

open access: yesmSphere, 2016
Classically, dormant endospores are defined by their resistance properties, particularly their resistance to heat. Much of the heat resistance is due to the large amount of dipicolinic acid (DPA) stored within the spore core.
Michael B. Francis, Joseph A. Sorg
doaj   +1 more source

Orbitofrontal cortex volume and brain reward response in obesity. [PDF]

open access: yes, 2015
Background/objectivesWhat drives overconsumption of food is poorly understood. Alterations in brain structure and function could contribute to increased food seeking.
Brown, MS   +6 more
core   +3 more sources

Compact Dilithium Implementations on Cortex-M3 and Cortex-M4

open access: yesIACR Transactions on Cryptographic Hardware and Embedded Systems, 2020
We present implementations of the lattice-based digital signature scheme Dilithium for ARM Cortex-M3 and ARM Cortex-M4. Dilithium is one of the three signature finalists of the NIST post-quantum cryptography competition. As our Cortex-M4 target, we use the popular STM32F407-DISCOVERY development board.
Greconici, Denisa O. C.   +2 more
openaire   +7 more sources

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Perfusion Fixation With Glutaraldehyde and Post-Fixation With Osmium Tetroxide for Electron Microscopy [PDF]

open access: yes, 1968
The conductivity of cerebral cortex drops during perfusion with glutaraldehyde in 5 min to about 60% of the original value, to remain unchanged during the subsequent 10-15 min of perfusion.
Khattab, F. I., van Harreveld, A.
core  

COMPARISON OF EMOTIONAL RESPONSES IN MONKEYS WITH RHINAL CORTEX OR AMYGDALA LESIONS [PDF]

open access: yes, 2002
Four emotionally arousing stimuli were used to probe the behavior of monkeys with bilateral ablations of the entorhinal and perirhinal cortex. The animals’ behavioral changes were then contrasted with those observed earlier (Meunier et al., 1999) in ...
Bachevalier, PhD Jocelyne   +1 more
core   +1 more source

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