Context Hydroxysafflor yellow A (HSYA) is the main bioactive ingredient of safflower (Carthamus tinctorius L., [Asteraceae]) for traumatic brain injury (TBI) treatment.Objective To explore the therapeutic effects and underlying mechanisms of HSYA on post-
En Hu+9 more
doaj +1 more source
Alterations of the giant pyramidal neurons (Betz cells) in brain cortex of rat offspring born from gestational diabetic dams: A morphometric study [Alteraciones de las Neuronas Piramidales Gigantes de la Corteza Cerebral en CrÃas de Ratas Nacidas de Hembras con Diabetes Gestacional: Un Estudio Morfométrico] [PDF]
A few studies reported the adverse effects of gestational diabetes on hippocampus and spinal cord of rat offspring. Giant pyramidal neurons are giant pyramidal neurons located in fifth layers of the gray matter in the primary motor cortex.
Ghafari, S.+2 more
core
Rule learning enhances structural plasticity of long-range axons in frontal cortex. [PDF]
Rules encompass cue-action-outcome associations used to guide decisions and strategies in a specific context. Subregions of the frontal cortex including the orbitofrontal cortex (OFC) and dorsomedial prefrontal cortex (dmPFC) are implicated in rule ...
Johnson, Carolyn+3 more
core +3 more sources
Magnetic ressonance imaging in the diagnosis of Creutzfeldt-Jakob disease: report of two cases
Creutzfeldt-Jacob disease (CJD) is a rare condition caused by a pathogenic prion protein that evolves with rapidly progressive dementia and death. The clinical presentation may sometimes be misleading. Magnetic Resonance Imaging (MRI) aids diagnosis with
Alan Peres Valente+2 more
doaj +1 more source
Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex
Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to determine how odor identity is encoded in olfactory cortex.
Benjamin Roland+4 more
doaj +1 more source
Vasoactive intestinal peptide-expressing (VIP) interneurons in the cortex regulate feedback inhibition of pyramidal neurons through suppression of somatostatin-expressing (SST) interneurons and, reciprocally, SST neurons inhibit VIP neurons. Although VIP
Daniel J Millman+15 more
doaj +1 more source
Oscillatory fluid flow drives scaling of contraction wave with system size [PDF]
Flows over remarkably long distances are crucial to the functioning of many organisms, across all kingdoms of life. Coordinated flows are fundamental to power deformations, required for migration or development, or to spread resources and signals. A ubiquitous mechanism to generate flows, particularly prominent in animals and amoeba, is acto-myosin ...
arxiv +1 more source
Mechanisms of spindle positioning. [PDF]
Accurate positioning of spindles is essential for asymmetric mitotic and meiotic cell divisions that are crucial for animal development and oocyte maturation, respectively.
McNally, Francis J
core +1 more source
Wrinkling of a spherical lipid interface induced by actomyosin cortex [PDF]
Actomyosin actively generates contractile forces that provide the plasma membrane with the deformation stresses essential to carry out biological processes. Although the contractile property of purified actomyosin has been extensively studied, to understand the physical contribution of the actiomyosin contractile force on a deformable membrane is still
arxiv +1 more source
Superior parietal cortex and the attention to delayed intention: An rTMS study. [PDF]
This study aimed to investigate whether the superior parietal cortex is causally involved in PM and, if so, what is its functional role. We applied repetitive transcranial magnetic stimulation (rTMS) to the left and right superior parietal cortex, and we
Bisiacchi, Patrizia+2 more
core +1 more source