Results 41 to 50 of about 97,779 (261)

What makes a frontal area of primate brain the frontal eye field?

open access: yesFrontiers in Integrative Neuroscience, 2015
The frontal eye field region (FEF) of the oculomotor pathways has been intensely studied. The primary goal of this review is to illustrate the phylogenetic displacement of the FEF locus in primate species. The locus is arrayed along the arcuate sulcus in
Pierre ePouget, Chantal eFrançois
doaj   +1 more source

Autonomous image segmentation and identification of anatomical landmarks from lumbar spine intraoperative computed tomography scans using machine learning: A validation study

open access: yesJournal of Craniovertebral Junction and Spine, 2020
Purpose: Machine-learning algorithms are a subset of artificial intelligence that have proven to enhance analytics in medicine across various platforms. Spine surgery has the potential to benefit from improved hardware placement utilizing algorithms that
Krzyzstof Siemionow   +3 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A connectional hub in the rostral anterior cingulate cortex links areas of emotion and cognitive control

open access: yeseLife, 2019
We investigated afferent inputs from all areas in the frontal cortex (FC) to different subregions in the rostral anterior cingulate cortex (rACC). Using retrograde tracing in macaque monkeys, we quantified projection strength by counting retrogradely ...
Wei Tang   +7 more
doaj   +1 more source

Cingulum bundle connectivity considering the double-layered cingulate cortex using diffusion-weighted MRI

open access: yesNeuroImage: Reports, 2021
The cingulum bundle (CB) is a fasciculus in the white matter surrounded by the cingulate cortex, which is generally subdivided into the anterior, middle, and posterior parts based on their function and cytology.
Sang-Han Choi   +4 more
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Study on root architecture of tropical chili peppers (Capsicum frutescens) inoculated with arbuscular mycorrhizal fungi

open access: yesHeliyon
The increasing biotic and abiotic stress on crop growth and development adversely affects crop productivity. Arbuscular Mycorrhizal Fungi (AMF) have garnered significant attention as an eco-friendly management technique, demonstrating multifaceted ...
Erlina Ambarwati   +5 more
doaj   +1 more source

Navigating the complex path between the oxytocin receptor gene (OXTR) and cooperation: an endophenotype approach

open access: yesFrontiers in Human Neuroscience, 2013
Although cooperation represents a core facet of human social behavior there exists considerable variability across people in terms of the tendency to cooperate.
Brian W. Haas   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy