Results 101 to 110 of about 2,329,584 (350)

Vertebral fractures are associated with increased cortical porosity in iliac crest bone biopsy of men with idiopathic osteoporosis [PDF]

, 2009
In men, vertebral fractures are poorly associated with bone density, and both cortical and trabecular micro-architectural changes could contribute to bone fragility.
A. Ostertag, C. Marty, D. Chappard, E. Legrand, M. Audran, M. Cohen-Solal, M.C. de Vernejoul   +6 more
core   +2 more sources

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Porous Titanium for Biomedical Applications: Evaluation of the Conventional Powder Metallurgy Frontier and Space-Holder Technique [PDF]

, 2019
Titanium and its alloys are reference materials in biomedical applications because of their desirable properties. However, one of the most important concerns in long-term prostheses is bone resorption as a result of the stress-shielding phenomena ...
Arévalo Mora, Cristina María, Lascano, Sheila, Montealegre-Meléndez, Isabel, Muñoz Moreno, Sergio, Rodríguez-Ortiz, José Antonio, Torres Hernández, Yadir, Torres Hernández, Yadir (Coordinador), Trueba Muñoz, Paloma   +7 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Insulin Resistance and the IGF-I-Cortical Bone Relationship in Children Ages 9-13 Years [PDF]

, 2017
IGF-I is a pivotal hormone in pediatric musculoskeletal development. Although recent data suggest that the role of IGF-I in total body lean mass and total body bone mass accrual may be compromised in children with insulin resistance, cortical bone ...
Ding, Ke-Hong, Gallant, Kathleen M. Hill, Hamrick, Mark W., Hausman, Dorothy B., Isales, Carlos M., Jenkins, Nathan T., Kindler, Joseph M., Laing, Emma M., Lewis, Richard D., Martin, Berdine R., McCabe, George P., Oshri, Assaf, Peacock, Munro, Pollock, Norman K., Warden, Stuart J., Weaver, Connie M.   +15 more
core   +1 more source

Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants

Advanced Healthcare Materials, EarlyView.
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay, Bryson White, Susmita Bose, Amit Bandyopadhyay   +3 more
wiley   +1 more source

Variability of Child Rib Bone Hounsfield Units using in vivo Computed Tomography [PDF]

, 2013
The variability assessment of the rib bone mechanical properties during the growth process is still missing. These properties could not be obtained in vivo on children.
BADINA, Alina, BERMOND, François, MITTON, David, SANDOZ, Baptiste, SIDELKEIR, Zaki, SKALLI, Wafa   +5 more
core   +4 more sources

The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice [PDF]

, 2016
There is strong evidence that vasodilatory nitric oxide (NO) donors have anabolic effects on bone in humans. Parathyroid hormone (PTH), the only osteoanabolic drug currently approved, is also a vasodilator.
Bukoski RD, Colleran PN, Collip JB, Kapitola J, Nickols GA, Ralston SH, Shymkiw RC   +6 more
core   +2 more sources

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow–derived counterparts

Journal of Tissue Engineering, 2016
In this study, we show that matrix dense cortical bone is the more potent compartment of bone than bone marrow as a stromal source for mesenchymal stem cells as isolated from adult rats. Lineage-depleted cortical bone-mesenchymal stem cells demonstrated >
Daniel Blashki, Matthew B Murphy, Mauro Ferrari, Paul J Simmons, Ennio Tasciotti   +4 more
doaj   +1 more source