Results 251 to 260 of about 2,329,584 (350)

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Evaluation of Mandibular Cortical Bone Density Changes Using CBCT During Accelerated Orthodontics with Low-Level Laser Therapy.

J Pharm Bioallied Sci
Rashid ME, Ibrahim T, Ghani AA, Alhodhudi A, Hajeer MY, Alam MK.   +5 more
europepmc   +1 more source

Relationship Between Facial Types and Alveolar Crest Cortical Bone Thickness and CT Values Determined by Multidetector Computed Tomography. [PDF]

Dent J (Basel)
Kitano M, Ota S, Iijima S, Ogura I.
europepmc   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Biomechanical effects of root/cortical bone relation on tooth movement during premolar-extraction space closure with clear aligners: a finite element study. [PDF]

Front Bioeng Biotechnol
Dong Y, Wang Y, Yang Z, Gong W, Guo M, Wu Y, Hu Y, Zheng L.   +7 more
europepmc   +1 more source

Biocompatibility and healing patterns in experimentally induced canine tibial fractures using Pedicle screw‐Rod external fixation

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that using a Pedicle screw‐Rod configuration for the external fixation of non‐articular tibial osteotomy aligns well with the principles of biological osteosynthesis, resulting in secondary bone healing characterized by callus formation and neovascularization.
Mohammad Mahdi Gooran, Ramin Mazaheri‐Khameneh, Seyed Mohammad Hashemi‐Asl, Rahim Hobbenaghi   +3 more
wiley   +1 more source

Inhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions. [PDF]

JCI Insight
Yu K, Vyavahare S, Alhamad D, Bensreti H, Ruan L, Tuladhar A, Dai C, Shaver JC, Tripathi A, Ding K, Pacholczyk R, Cooley MA, Zhong R, Johnson MH, Chen J, Bollag WB, Isales CM, Hill WD, Hamrick MW, Fulzele S, McGee-Lawrence ME.   +20 more
europepmc   +1 more source

Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis

Animal Models and Experimental Medicine, EarlyView.
This study developed a biosafe, accessible, and versatile murine model of bone TB using Mycobacterium smegmatis, a fast‐growing, nonpathogenic mycobacterial species with high genomic homology to Mycobacterium tuberculosis. Three infection routes—subperiosteal calvarial injection, intratibial injection, and intracardiac (left ventricular) inoculation ...
Yewei Jia, Yuhuai Guo, Yusheng Yang, Jie Zhang, Ziyang Zhang, Ying Qu, Jiulin Tan, Jie Shen, Nathachit Limjunyawong, Jianzhong Xu, Zehua Zhang, Fei Luo, Ce Dou   +12 more
wiley   +1 more source

Prediction of biomechanical properties of ex vivo human femoral cortical bone using Raman spectroscopy and machine learning algorithms. [PDF]

Bone Rep
Unal M, Unlu R, Uppuganti S, Nyman JS.
europepmc   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

Annals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf, Maria Eveslage, Timo Wirth, Christian Wünsch, Eva M. Schumann, Jan D. Lünemann, Heinz Wiendl, Luisa Klotz, Nicholas Schwab   +8 more
wiley   +1 more source