Results 51 to 60 of about 118,658 (298)

Phase of beta-frequency tACS over primary motor cortex modulates corticospinal excitability

, 2018
The assessment of corticospinal excitability by means of transcranial magnetic stimulation-induced motor evoked potentials is an established diagnostic tool in neurophysiology and a widely used procedure in fundamental brain research.
De Gelder, B., De Graaf, T., Engelen, T., Sack, A., Schilberg, L., Schuhmann, T., Ten Oever, S.   +6 more
core   +1 more source

Inhomogeneous cortical synchronization and partial epileptic seizures [PDF]

, 2014
Objective: Interictal synchronization clusters have recently been described in several publications using diverse techniques, including neurophysiological recordings and fMRI, in patients suffering from epilepsy.
García de Sola, Rafael, Ortega, Guillermo José, Pastor, Jesús Eduardo, Vega Zelaya, Lorena   +3 more
core   +1 more source

Cortical excitability in migraine [PDF]

The Journal of Headache and Pain, 2000
Cortical hyperexcitability in migraine has been suggested to play a pivotal role in triggering migraine attacks, possibly via generation of spreading depression. Low levels of plasma, intracellular and brain magnesium as well as increased amplitudes of visual evoked potentials support this theory. More recent data on evoked and even related potentials,
openaire   +1 more source

Understanding Epileptiform After-Discharges as Rhythmic Oscillatory Transients [PDF]

, 2017
Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same patient, wide variability in the duration of transient response has been ...
Baier, Gerold, Taylor, Peter N, Wang, Yujiang   +2 more
core   +2 more sources

Plasticity and dystonia: a hypothesis shrouded in variability. [PDF]

, 2020
Studying plasticity mechanisms with Professor John Rothwell was a shared highlight of our careers. In this article, we discuss non-invasive brain stimulation techniques which aim to induce and quantify plasticity, the mechanisms and nature of their ...
A Albanese, A Berardelli, A Conte, A Guerra, A Guerra, A Karabanov, A Karabanov, A Latorre, A Quartarone, A Quartarone, A Quartarone, A Quartarone, A Quartarone, A Quartarone, A Sadnicka, A Sadnicka, A Sadnicka, Anna Sadnicka, B Balint, B Cheeran, B Hordacre, C Ganos, C Terranova, D Belvisi, D Weise, F Fratello, F Pierelli, G Abbruzzese, H Eggink, HA Jinnah, HR Siebner, JF Muller-Dahlhaus, JS Kang, K Stefan, KM Fedak, KP Bhatia, L Ozelius, M Hamada, M Hamada, M Kojovic, M Pellegrini, Masashi Hamada, MC Ridding, N Patel, NH Jung, RG Carson, S Meunier, S Wiethoff, SA Schneider, V Lopez-Alonso, V Lopez-Alonso, YZ Huang, YZ Huang   +52 more
core   +1 more source

Neurophysiological Mechanisms Underlying Cortical Hyper-Excitability in Amyotrophic Lateral Sclerosis: A Review

Brain Sciences, 2021
Amyotrophic lateral sclerosis (ALS) is a progressive neuromotor disease characterized by the loss of upper and lower motor neurons (MNs), resulting in muscle paralysis and death. Early cortical hyper-excitability is a common pathological process observed
Jonu Pradhan, Mark C. Bellingham
doaj   +1 more source

Cortical excitability following passive movement

Physical Therapy Research, 2018
In brain injury rehabilitation, passive movement exercises are frequently used to maintain or improve mobility and range of motion. They can also induce beneficial and sustained neuroplastic changes. Neuroimaging studies have revealed that passive movements without motor commands activate not only the primary somatosensory cortex but also the primary ...
openaire   +3 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

TRPV1 Channels Regulate Cortical Excitability in Humans [PDF]

The Journal of Neuroscience, 2012
Studies in rodents show that transient receptor potential vanilloid 1 (TRPV1) channels regulate glutamate release at central and peripheral synapses. In humans, a number of nonsynonymous single-nucleotide polymorphisms (SNPs) have been described in theTRPV1gene, and some of them significantly alter the functionality of the channel.
Mori F., Ribolsi M., Kusayanagi H., Monteleone F., Mantovani V., Buttari F., Marasco E., Bernardi G., Maccarrone M., Centonze D.   +9 more
openaire   +7 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source