Results 51 to 60 of about 68,479 (299)

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Cortical excitability on sleep deprivation measured by transcranial magnetic stimulation: A systematic review and meta-analysis

Brain Research Bulletin
Sleep deprivation is a common public problem, and researchers speculated its neurophysiological mechanisms related to cortical excitatory and inhibitory activity.
Yihui Zhang, Yuan Shi, Ye Zhang, Jian Jiao, Xiangdong Tang   +4 more
doaj   +1 more source

Transcranial Magnetic Stimulation for the treatment of tinnitus: Effects on cortical excitability

BMC Neuroscience, 2007
Background Low frequency repetitive transcranial magnetic stimulation (rTMS) has been proposed as an innovative treatment for chronic tinnitus. The aim of the present study was to elucidate the underlying mechanism and to evaluate the relationship ...
Hajak Göran, Sand Philipp G, Binder Harald, Marienhagen Joerg, Kleinjung Tobias, Langguth Berthold, Eichhammer Peter   +6 more
doaj   +1 more source

Sleep-dependent upscaled excitability, saturated neuroplasticity, and modulated cognition in the human brain

eLife, 2022
Sleep strongly affects synaptic strength, making it critical for cognition, especially learning and memory formation. Whether and how sleep deprivation modulates human brain physiology and cognition is not well understood.
Mohammad Ali Salehinejad, Elham Ghanavati, Jörg Reinders, Jan G Hengstler, Min-Fang Kuo, Michael A Nitsche   +5 more
doaj   +1 more source

Slow Cortical Potentials Reflect the Regulation of Cortical Excitability [PDF]

, 1993
A model is described which postulates ways in which regulatory circuits within the brain might generate electrical activity underlying spontaneous EEG fluctuations and event-related slow potentials (ERP) of the brain. We suggest that slow potentials represent a measure of the excitability of cortical neuronal networks and that this excitability must be
openaire   +2 more sources

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Exploring the Modulation of Motor Cortical Excitability by Duration of Transcranial Direct Current Stimulation [PDF]

, 2023
The motor cortex(MC) was important in human learning and memory, and the level of cortical excitability is a way of assessing its state. To non-invasively modulate cortical excitability, transcranial direct current stimulation (tDCS) is a widely employed
Liu, Xiaohui
core  

Upside down crossed-cerebellar diachisis: Proposing chronic stimulation of the dentatothalamocortical pathway for post-stroke motor recovery.

Frontiers in Integrative Neuroscience, 2012
Background: Stroke remains the leading cause for long-term motor impairment in the industrialized world. New techniques are needed to improve outcomes.Objective: To propose chronic electrical stimulation of the dentatothalamocortical pathway as a method ...
Andre eMachado, Kenneth B Baker
doaj   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

The cortical mechanisms underlying the analgesic effects of repetitive transcranial magnetic stimulation: protocol for a systematic review and meta-analysis

Systematic Reviews
Introduction Repetitive transcranial magnetic stimulation (rTMS) is a promising, safe, and non-invasive treatment for pain. However, there is no clear understanding of the cortical mechanisms underlying the analgesic effect of rTMS.
Nahian S. Chowdhury, Donovan Cheng, Wei-Ju Chang, Negin Hesam-Shariati, Yann Quide, Pedro Henrique Martins da Cunha, Jorge Dornellys da Silva Lapa, Gabriel Taricani Kubota, Karlos Daniell Araújo dos Santos, Davi Neves Coelho, Daniel Ciampi de Andrade, Sylvia Gustin   +11 more
doaj   +1 more source