Results 161 to 170 of about 1,266,044 (253)

Air pollution is linked to divergent cortical thickness patterns in brain regions vulnerable to Alzheimer's disease. [PDF]

Neurotoxicology
Salminen LE, Wang X, Petkus AJ, Fennema-Notestine C, Elman JA, Hagler DJ, Kaufman JD, Millstein J, Braskie MN, Liu J, Cho HJ, Kothapalli D, Thompson PM, Beavers DP, Espeland MA, Gatz M, Resnick SM, Frahmand I, Rapp SR, Finch CE, Chen JC, Kremen WS, Franz CE.   +22 more
europepmc   +1 more source

The Possibility of Determining Osteoporosis by Analysing the Medical Images of the Cortical Bone

This paper proposes a method of bone structure analysis that could be used to determine if a person has osteoporosis by analysing the cortical bone on medical images. Osteoporosis is a bone disease that leads to an increased risk of fracture. This method
Glazs, Aleksandrs, Kovaļovs, Mihails
core  

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Reduced cortical thickness in individuals with congenital adrenal hyperplasia (CAH). [PDF]

Sci Rep
Luders E, Spencer D, Hughes IA, Thankamony A, Srirangalingam U, Gleeson H, Hines M, Kurth F.   +7 more
europepmc   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

Advanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku, Jinwon Kwon, Nara Yoon, Hyung Kwon Byeon, Jaemoon Yang   +4 more
wiley   +1 more source

Compensating cortical thickness for cortical folding-related variation. [PDF]

Imaging Neurosci (Camb)
Demirci N, Coalson TS, Holland MA, Van Essen DC, Glasser MF.   +4 more
europepmc   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing

Advanced Science, EarlyView.
A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang, Lei Zhao, Haoyuan Yao, Qiongshan Zhang, Fuzhen Xuan, Bin Zhang   +5 more
wiley   +1 more source

Renal Cortical Thickness and Derived Ratios as Superior Ultrasonographic Markers for Detecting Feline Chronic Kidney Disease. [PDF]

Vet Radiol Ultrasound
Sakulsirajit R, Kasemsuwan T, Saisawart P, Sutthigran S, Wanglerm A, Kornpiboonpong S, Choisunirachon N, Thanaboonnipat C.   +7 more
europepmc   +1 more source