Pharmacological interventions in corticobasal degeneration: a review [PDF]
Dementia & Neuropsychologia, 2020 . Corticobasal degeneration (CBD) is a sporadic tauopathy that presents with a varied combination of motor, cognitive, and behavioral features, making its diagnosis difficult.
Leonardo Caixeta +3 more
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An autopsy-proven case of Corticobasal degeneration heralded by Pontine infarction [PDF]
BMC Neurology, 2021 Background Neurodegenerative disorders are characterized by insidious progression with poorly-delineated long latent period. Antecedent clinical insult could rarely unmask latent neurodegenerative disorders.
Dallah Yoo +3 more
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Corticobasal degeneration and corticobasal syndrome: A review [PDF]
Clinical Parkinsonism & Related Disorders, 2019 Corticobasal degeneration (CBD) is a rare neurodegenerative disorder. The most common presentation of CBD is the corticobasal syndrome (CBS), which is a constellation of cortical and extrapyramidal symptoms and signs.
Vasilios C. Constantinides +4 more
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Progressive supranuclear palsy and corticobasal degeneration: novel clinical concepts and advances in biomarkers [PDF]
Arquivos de Neuro-Psiquiatria, 2022 Background: Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic adult-onset primary tauopathies clinically classified among the atypical parkinsonian syndromes.
Jacy Bezerra Parmera +3 more
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Coenzyme Q10 Levels Are Decreased in the Cerebellum of Multiple-System Atrophy Patients. [PDF]
PLoS ONE, 2016 BackgroundThe objective of this study was to evaluate whether the levels of coenzyme Q10 (CoQ10) in brain tissue of multiple system atrophy (MSA) patients differ from those in elderly controls and in patients with other neurodegenerative diseases ...
Lucia V Schottlaender +7 more
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Neuropsychiatric disturbances in atypical parkinsonian disorders [PDF]
Neuropsychiatric Disease and Treatment, 2018 Daniele Belvisi,1 Isabella Berardelli,2 Antonio Suppa,1,3 Andrea Fabbrini,3 Massimo Pasquini,3 Maurizio Pompili,2 Giovanni Fabbrini1,3 1IRCCS Neuromed, Pozzilli, Italy; 2Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention ...
Belvisi D +6 more
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Corticobasal degeneration preceded by cognitive impairment and apathy: An autopsy case report [PDF]
PCN ReportsBackground Corticobasal degeneration (CBD) presents with a range of clinical phenotypes, making diagnosis challenging. We report the clinical course of a patient with autopsy‐confirmed CBD who initially presented with cognitive impairment and apathy ...
Shoma Hirose +6 more
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Dynamic aphasia as an early sign of corticobasal degeneration: Clinico-radio-pathological correlation [PDF]
eNeurologicalSciA 72-year-old man presented with a 6-month history of decreased voluntary speech. Sparse speech and decreased word fluency were observed. Articulation, naming, comprehension, and repetition were preserved.
Masanori Kurihara +11 more
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MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features [PDF]
Acta Neuropathologica Communications, 2020 The microtubule-associated protein tau (MAPT) H1 haplotype is the strongest genetic risk factor for corticobasal degeneration (CBD). However, the specific H1 subhaplotype association is not well defined, and it is not clear whether any MAPT haplotypes ...
Rebecca R. Valentino +14 more
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A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies [PDF]
Stem Cell Reports, 2019 Summary: Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments.
Celeste M. Karch +54 more
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