Results 91 to 100 of about 15,044 (185)

The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts

Neurobiology of Disease, 2007
Previously we have shown that the H1c haplotype on the background of the H1 clade of haplotypes at the MAPT locus is associated with increased risk for progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Alzheimer’s disease (AD ...
Amanda J. Myers, Alan M. Pittman, Alice S. Zhao, Kristen Rohrer, Mona Kaleem, Lauren Marlowe, Andrew Lees, Doris Leung, Ian G. McKeith, Robert H. Perry, Chris M. Morris, John Q. Trojanowski, Christopher Clark, Jason Karlawish, Steve Arnold, Mark S. Forman, Vivianna Van Deerlin, Rohan de Silva, John Hardy   +18 more
doaj   +1 more source

Early and Differential Diagnosis of Dementia and Mild Cognitive Impairment Design and Cohort Baseline Characteristics of the German Dementia Competence Network [PDF]

, 2009
Background: The German Dementia Competence Network (DCN) has established procedures for standardized multicenter acquisition of clinical, biological and imaging data, for centralized data management, and for the evaluation of new treatments.
Frölich, Lutz, Gertz, Hermann-Josef, Hampel, Harald, Henn, Fritz, Heuser, Isabella, Huell, Michael, Jahn, Holger, Jessen, Frank, Kornhuber, Johannes, Luckhaus, Christian, Maier, Wolfgang, Pantel, Johannes, Perneczky, Robert, Peters, Oliver, Rienhoff, Otto, Ruüther, Eckart, Schmidtke, Klaus, Schroeder, Johannes, Seuchter, Susanne A., Weih, Markus, Wiltfang, Jens, Wolf, Stefanie   +21 more
core   +1 more source

Behavioral and Neurophysiological Effects of Transdermal Rotigotine in Atypical Parkinsonism [PDF]

, 2014
Effective therapies for the so-called atypical parkinsonian syndrome (APS) such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), or corticobasal syndrome (CBS) are not available.
Davide Vito Moretti, Giovanni Battista Frisoni, Giuliano Binetti, Orazio Zanetti   +3 more
core   +2 more sources

Apraxia in Corticobasal Degeneration

Brain and Cognition, 1999
Corticobasal degeneration (CBD) is a degenerative disease that often presents with an asymmetric progressive ideomotor limb apraxia. Some apraxic subjects may fail to perform skilled purposive movements on command because they have lost the memories or representations that specify how these movements should be performed (representational deficit).
Memory Disorders Clinic, Orlando Regional Healthcare System, Orlando, Florida ( host institution ), Jacobs, Daniel H. ( author ), Adair, John C. ( author ), Macauley, Beth ( author ), Gold, Michael ( author ), Gonzalez Rothi, Leslie J. ( author ), Heilman, Kenneth M. ( author )   +6 more
openaire   +3 more sources

A Corticobasal Syndrome Variant of Familial Creutzfeldt-Jakob Disease with Stroke-Like Onset

Case Reports in Neurological Medicine, 2016
Creutzfeldt-Jakob disease (CJD) is an untreatable rare human prion disease characterized by rapidly progressive dementia along with various neurological features, including myoclonus and sometimes other movement disorders.
Ján Necpál, Martin Stelzer, Silvia Koščová, Michal Patarák   +3 more
doaj   +1 more source

The Language Profile of Behavioral Variant Frontotemporal Dementia [PDF]

, 2016
BACKGROUND: The language profile of behavioral variant frontotemporal dementia (bvFTD) remains to be fully defined. OBJECTIVE: We aimed to quantify the extent of language deficits in this patient group.
Buckley, AH, Crutch, SJ, Downey, LE, Hardy, CJ, Lehmann, M, Rohrer, JD, Varley, RA, Warren, JD, Warrington, EK, Zimmerer, VC   +9 more
core   +1 more source

Rates of lobar atrophy in asymptomatic MAPT mutation carriers. [PDF]

, 2019
IntroductionThe aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule-associated protein tau (MAPT) mutation carriers.MethodsMAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill R, Jack, Clifford R, Jones, David T, Kantarci, Kejal, Knopman, David S, Kremers, Walter K, Lapid, Maria, LEFFTDS Consortium, Lesnick, Timothy G, Rademakers, Rosa, Rosen, Howie, Senjem, Matthew, Syrjanen, Jeremy, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +24 more
core   +2 more sources

Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology [PDF]

, 2018
Microglial cells are crucial players in the pathological process of neurodegenerative diseases, such as Alzheimer’s disease (AD). Microglial response in AD has been principally studied in relation to amyloid-beta pathology but, comparatively, little is
Fernández Valenzuela, Juan José, Gutiérrez, Antonia, Jiménez Muñoz, Sebastián, Muñoz Castro, Clara, Navarro Garrido, Victoria, Romero Molina, Carmen, Sánchez Mico, María, Sánchez Varo, Raquel María, Vitorica Ferrández, Francisco Javier, Vizuete Chacón, María Luisa   +9 more
core   +2 more sources

Levodopa-responsive depression associated with corticobasal degeneration: a case report

Neuropsychiatric Disease and Treatment, 2017
Natsumi Tarakita,1 Haruo Nishijima,2 Norio Yasui-Furukori1 1Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, 2Department of Neurology, Aomori Prefectural Central Hospital, Aomori, Japan Abstract: A 60-year-old ...
Tarakita N, Nishijima H, Yasui-Furukori N   +2 more
doaj  

Cerebrospinal Fluid Total and Phosphorylated Tau Protein in Behavioral Variant Frontotemporal Dementia, Progressive Supranuclear Palsy, Corticobasal Syndrome and Non-Fluent Agrammatic Primary Progressive Aphasia: A Systematic Review and Meta-Analysis

Biomedicines
(1) Background: Frontotemporal lobar degeneration (FTLD) is a generic term which refers to multiple pathologies, including FTLD-tau. The most common FTLD-tau diseases are Pick’s disease (PiD), progressive supranuclear palsy (PSP) and corticobasal ...
Nikolaos Giagkou, Ioanna Kapsali, Maria-Evgenia Brinia, Vasilios C. Constantinides   +3 more
doaj   +1 more source