Results 41 to 50 of about 15,044 (185)
Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]
In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc +5 more
core +1 more source
CORTICO-BASAL DEGENERATION (CLINICAL CASE)
The article presents a clinical case of cortico-basal degeneration. The complexity of the diagnosis and treatment of this complication is demonstrated.
Светлана Алексеевна Зуева +4 more
doaj
Estimating frontal and parietal involvement in cognitive estimation: a study of focal neurodegenerative diseases [PDF]
We often estimate an unknown value based on available relevant information, a process known as cognitive estimation. In this study, we assess the cognitive and neuroanatomic basis for quantitative estimation by examining deficits in patients with focal ...
Christopher A. Olm +8 more
core +2 more sources
Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W +8 more
core +1 more source
Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. [PDF]
We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60's followed by memory impairment, low mood and recurrent falls.
Hardy, J +8 more
core +2 more sources
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl +10 more
wiley +1 more source
Cognitive dysfunction in corticobasal degeneration
Corticobasal degeneration (CBD) was originally described as a distinct clinicopathological entity in 1967. Since then, different phenotypic presentations have emerged as possible manifestations of CBD histopathological findings.
Laís Machado de Oliveira +3 more
doaj +1 more source
Ultrassonografia transcraniana na doença de Parkinson [PDF]
Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure.
Andrade, Daniel Ciampi De +6 more
core +1 more source
Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt +82 more
wiley +1 more source
Diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT: a clinical follow up study [PDF]
The [(123)I]ioflupane—a dopamine transporter radioligand—SPECT (DaT-SPECT) has proven to be useful in the differential diagnosis of tremor. Here, we investigate the diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT.
Arias Carrión, Óscar +4 more
core +1 more source

