Results 41 to 50 of about 15,044 (185)

Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]

open access: yes, 2005
In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc   +5 more
core   +1 more source

CORTICO-BASAL DEGENERATION (CLINICAL CASE)

open access: yesМать и дитя в Кузбассе, 2020
The article presents a clinical case of cortico-basal degeneration. The complexity of the diagnosis and treatment of this complication is demonstrated.
Светлана Алексеевна Зуева   +4 more
doaj  

Estimating frontal and parietal involvement in cognitive estimation: a study of focal neurodegenerative diseases [PDF]

open access: yes, 2015
We often estimate an unknown value based on available relevant information, a process known as cognitive estimation. In this study, we assess the cognitive and neuroanatomic basis for quantitative estimation by examining deficits in patients with focal ...
Christopher A. Olm   +8 more
core   +2 more sources

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]

open access: yes, 2019
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W   +8 more
core   +1 more source

Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. [PDF]

open access: yes, 2014
We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60's followed by memory impairment, low mood and recurrent falls.
Hardy, J   +8 more
core   +2 more sources

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl   +10 more
wiley   +1 more source

Cognitive dysfunction in corticobasal degeneration

open access: yesArquivos de Neuro-Psiquiatria
Corticobasal degeneration (CBD) was originally described as a distinct clinicopathological entity in 1967. Since then, different phenotypic presentations have emerged as possible manifestations of CBD histopathological findings.
Laís Machado de Oliveira   +3 more
doaj   +1 more source

Ultrassonografia transcraniana na doença de Parkinson [PDF]

open access: yes, 2012
Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure.
Andrade, Daniel Ciampi De   +6 more
core   +1 more source

Individualized Atrophy‐Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed‐Effects Modeling

open access: yesAnnals of Neurology, EarlyView.
Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt   +82 more
wiley   +1 more source

Diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT: a clinical follow up study [PDF]

open access: yes, 2014
The [(123)I]ioflupane—a dopamine transporter radioligand—SPECT (DaT-SPECT) has proven to be useful in the differential diagnosis of tremor. Here, we investigate the diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT.
Arias Carrión, Óscar   +4 more
core   +1 more source

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