Results 71 to 80 of about 15,044 (185)
The Journal of Physiology, EarlyView.Abstract figure legend Hypocapnic hyperventilation reduced end‐tidal carbon dioxide partial pressure and middle cerebral artery mean velocity, and impaired oculomotor response by modulating visual fixation and anti‐saccadic control. Hyperventilation itself also impaired anti‐saccadic control.
Yusei Yoshimura +4 more
wiley +1 more source
From mechanism to phenotype: What fits in a basket trial
Epilepsia, EarlyView.
Kette D. Valente
wiley +1 more source
Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 1, March 2026.Abstract INTRODUCTION Frontotemporal dementia (FTD) is the most common dementia in people under age 60. Although FTD is often characterized by behavioral symptoms, few national interventions address management of these symptoms. Here we describe our protocol for Support via Technology: Living and Learning with Advancing FTD (STELLA‐FTD), an ...
Allison Lindauer +7 more
wiley +1 more source
Síndromes parkinsónicas degenerescência corticobasal : estudo clínico imagiológico com IIC-raclopride [PDF]
, 2014 Trabalho final de mestrado integrado em Medicina (Neurologia), apresentada á Faculdade de Medicina da Universidade de CoimbraA degenerescência corticobasal (DCB) é uma enfermidade neurodegenerativa rara, progressiva, englobada num conjunto de patologias ...
Martinho, Sérgio Miguel
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Classification of tauopathies from human brain homogenates through salt‐modulated tau amplification
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION Tauopathies are a heterogeneous group of neurodegenerative disorders defined by abnormal aggregation of tau protein. Although cryogenic electron microscopy (cryo‐EM) has uncovered disease‐specific tau structures, translating these insights into diagnostic tools remains difficult. METHODS We developed a heparin‐free, salt‐modulated
Alessia Santambrogio +8 more
wiley +1 more source
Frontrunner in Translation: Progressive Supranuclear Palsy
Frontiers in Neurology, 2019 Progressive supranuclear palsy (PSP) is a four-repeat tau proteinopathy. Abnormal tau deposition is not unique for PSP and is the basic pathologic finding in some other neurodegenerative disorders such as Alzheimer's disease (AD), age-related tauopathy ...
Ali Shoeibi, Nahid Olfati, Irene Litvan
doaj +1 more source
Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]
, 2019 Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F +22 more
core +3 more sources
Greater locus coeruleus vulnerability in atypical clinicopathologic forms of Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION The locus coeruleus (LC) degenerates early in Alzheimer's disease (AD). However, the extent of rostrocaudal degeneration across clinicopathologic heterogeneity remains underexplored in AD. METHODS Using digital pathology, we quantified LC neuronal density and area at three neuroanatomic levels in a large AD series.
Sara Rose Dunlop +16 more
wiley +1 more source
npj Parkinson's Disease, 2017 Differential diagnosis: imaging to tell the difference Brain imaging could be used to distinguish between patients with corticobasal degeneration (CBD) and Parkinson's disease (PD).
Franziska Albrecht +4 more
doaj +1 more source
A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau deposition [PDF]
, 2017 We have studied a family with severe mental retardation characterized by the virtual absence of speech, autism spectrum disorder, epilepsy, late-onset ataxia, weakness and dystonia.
Feldman, Gerald +9 more
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