Results 261 to 270 of about 334,842 (343)

Analysis of the Clinical Value of Monocyte Human Leukocyte Antigen‐DR, Procalcitonin, and C‐Reactive Protein in Sepsis

open access: yesiLABMED, EarlyView.
This study compared the clinical value of monocytic human leukocyte antigen‐DR (mHLA‐DR), procalcitonin (PCT), and C‐reactive protein (CRP) in diagnosing and predicting sepsis outcomes, providing better guidance for clinical management. The diagnostic efficacy of PCT and CRP for sepsis was superior to that of mHLA‐DR, but mHLA‐DR demonstrated a ...
Jingxiao Dong   +4 more
wiley   +1 more source

Temporal response patterns of human gut microbiota to dietary fiber

open access: yesiMeta, EarlyView.
In this study, 19 overweight participants, with or without type 2 diabetes mellitus, underwent 14 days of normal‐diet observation followed by 14 days of dietary fiber intervention. Fecal samples and continuous glucose monitoring data were collected daily throughout the 28‐day period.
Xiaotong Lin   +5 more
wiley   +1 more source

Systemic fat embolism after renal homotransplantation and treatment with corticosteroids

open access: bronze, 1966
Jessica Jones   +2 more
openalex   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

open access: yesInterdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao   +6 more
wiley   +1 more source

Human Platelet Lysate Treatment for Exposure Keratopathy: An In Vivo Confocal Microscopy and Anterior Segment OCT Study. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Tsai CY   +7 more
europepmc   +1 more source

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller   +4 more
wiley   +1 more source

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately‐to‐Severely Active Crohn's Disease

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study aimed to characterize the pharmacokinetics (PK) of etrolizumab, an IgG1‐humanized monoclonal anti‐β7 integrin antibody, and assess its exposure–response (ER) relationship for key clinical outcomes in patients with moderately‐to‐severely active Crohn's disease.
Anita Moein   +4 more
wiley   +1 more source

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