Results 281 to 290 of about 686,098 (387)

Distinctive genetic architecture of infantile epileptic spasms syndrome compared to self‐limited infantile epilepsy by trios whole‐exome sequencing

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile epileptic spasms syndrome (IESS) and self‐limited infantile epilepsy (SeLIE) are both genetically heterogeneous disorders during infancy with distinct prognoses. To better define the genetic spectrum of IESS, we performed a comparative genetic analysis using SeLIE cases as a reference group. Methods We performed whole‐exome
Yihong Sun   +6 more
wiley   +1 more source

Current Non-operative Management of Shoulder Pathologies: A Narrative Review. [PDF]

open access: yesCureus
Vargas-Figueroa RA   +4 more
europepmc   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

open access: yesFlavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan   +9 more
wiley   +1 more source

Predicting nephrotic syndrome outcomes in children using machine learning: insights from a cross-sectional study. [PDF]

open access: yesBMC Nephrol
Mohebbi H   +6 more
europepmc   +1 more source

Rutaceae Zanthoxylum–Derived 7‐Demethylsuberosin Alleviates the Rheumatoid Arthritis Through Inhibiting the Maturation of Dendritic Cells via Targeting MAPK14 Functional Food‐Based 7‐Demethylsuberosin

open access: yesFood Frontiers, EarlyView.
This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han   +7 more
wiley   +1 more source

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx

open access: yesHead &Neck, EarlyView.
ABSTRACT Background University of Michigan Cancer Center (UMCC) protocol 9520 treated stage III/IV locally advanced squamous cell carcinoma of the larynx (LASCCL) with cisplatin and 5‐fluorouracil to select for definitive therapy based on response.
Zachary Risch   +19 more
wiley   +1 more source

Ischemia of the Tongue and Scalp as an Uncommon Presentation of Giant Cell Arteritis. [PDF]

open access: yesEur J Case Rep Intern Med
Reis CS   +6 more
europepmc   +1 more source

Comparative evaluation of oral corticosteroids versus low molecular weight heparin in the treatment of lichen planus

open access: diamond, 2019
Narendar Gajula   +3 more
openalex   +2 more sources

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai   +4 more
wiley   +1 more source

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