Results 31 to 40 of about 313,604 (267)

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Acute Pathophysiological Effects of Intratracheal Instillation of Budesonide and Exogenous Surfactant in a Neonatal Surfactant-depleted Piglet Model

Pediatrics and Neonatology, 2010
Chronic lung disease continues to be a major complication in premature infants with severe respiratory distress syndrome (RDS). This is despite having advanced ventilatory care, prenatal corticosteroids, and postnatal surfactant therapies.
Chia-Feng Yang, Mei-Jy Jeng, Wen-Jue Soong, Yu-Sheng Lee, Pen-Chen Tsao, Ren-Bin Tang   +5 more
doaj   +1 more source

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Comparing Intra-Articular Corticosteroids and Platelet-rich Plasma for Knee Osteoarthritis Pain: A Prospective Quasi-comparative Study

Indian Journal of Pain
Background and Aim: Intra-articular (I/A) corticosteroids (CS) are used for short to mid-term pain relief in knee osteoarthritis (KOA). Newer therapies such as platelet-rich plasma (PRP) are believed to induce regenerative changes and decrease pain. Ours
Khuboo Rana, Suruchi Ambasta, Shivani Rastogi, Suraj Kumar, Shamrendra Narayan, Anurag Agarwal   +5 more
doaj   +1 more source

An Early Intensive Intervention for Inducing Inactive Asthma in Adults —A One-Year Follow-Up Observation Study—

Allergology International, 2011
Background: Treatment strategy that reduces dependence on long-term medication for chronic asthma is preferable. The purpose of the study is to investigate the efficacy of an early intensive intervention for inducing inactive asthma in adults and ...
Koichiro Kudo, Hiroko Arioka, Yuichiro Takeda, Takuro Shimbo, Satoko Handa, Akihiko Kawana, Mitsuhiro Kamimura, Yasuhiro Yamauchi, Hiroyuki Nagase, Nobuyuki Kobayashi, Toshie Manabe, Junzaburo Kabe   +11 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Successful management of chronic eosinophilic pneumonia triggered by immune checkpoint inhibitor: a case report and literature review

Frontiers in Immunology
Immune checkpoint inhibitors (ICIs) enhance antitumor immunity by blocking inhibitory immune signals, but can lead to immune-related adverse events (irAEs). Therefore, effective management of irAEs is crucial during ICI therapy.
Yasuhito Suzuki, Junpei Saito, Satoshi Kubota, Masakazu Ikeda, Mami Rikimaru, Ryuki Yamada, Takahiro Kumanaka, Ryutaro Tanaka, Kentaro Kazama, Koshi Saito, Rina Harigane, Riko Sato, Hikaru Tomita, Natsumi Watanabe, Takashi Umeda, Ryuichi Togawa, Yuki Sato, Takefumi Nikaido, Xintao Wang, Kenya Kanazawa, Yoshinori Tanino, Shigeyuki Murono, Yoko Shibata   +22 more
doaj   +1 more source

Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial

Journal of Pharmacopuncture, 2020
Objectives: Atopic dermatitis (AD) is a prevalent and chronic, pruritic inflammatory skin condition that can influence all age groups. AD is associated with a poor health-related quality of life.
Yunes Panahi, Nassim Rastgar, Ali Zamani, Amirhossein Sahebkar   +3 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A Systematic Review of Treatment for Acute Interstitial Nephritis

Kidney International Reports
Introduction: Acute interstitial nephritis (AIN) is a common cause of acute kidney injury. It is characterized by tubular inflammation with eosinophils histologically.
Yalin Yu, Erik Biros, Xiao Chang, Andrew J. Mallett   +3 more
doaj   +1 more source